Work on this instrument grew out of research on newborn assessment and training for the Perinatal-20 project, a set of 20 National Institute on Drug Abuse (NIDA)-sponsored intervention studies of cocaineand other substance-abusing mothers, and the specific requirements of research on the Maternal Lifestyles Study, a National Institute of Child Health and Human Development-sponsored multisite st...

S search is the mechanism whereby advertisers pay a fee to Internet search engines to be displayed alongside organic (nonsponsored) web search results. Based on prior literature, we draw an analogy between these markets and financial markets. We use the analogy as well as the key differences to present a theoretical framework consisting of a set of research questions about the pricing of keywor...

Selective reporting is prevalent in the medical literature, particularly in industry-sponsored research. In this paper, we expose selective reporting that is not evident without access to internal company documents. The published report of study 329 of paroxetine in adolescents sponsored by GlaxoSmithKline claims that “paroxetine is generally well tolerated and effective for major depression in...

BACKGROUND Submission of study protocols to research ethics committees (RECs) constitutes one of the earliest stages at which planned trials are documented in detail. Previous studies have investigated the amendments requested from researchers by RECs, but the type of issues raised during REC review have not been compared by sponsor type. The objective of this study was to identify recurring sh...

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