INTRODUCTION Two decades ago tropical sprue, Immunoproliferative Small Intestinal Disease (IPSID) and infections were common causes of malabsorption in India. It is possible that implementation of preventive health measures and improved sanitation may have changed the spectrum of disorders causing malabsorption. The aim of this study therefore was to assess the spectrum of malabsorption seen at...

Jones, T. C. (Rockefeller University, New York, N. Y. 10021), A. G. Dean and G. W. Parker. Seasonal gastroenteritis and malabsorption at an American military base in the Philippines. II. Malabsorption following the acute illness. Am J Epidemiol 95: 128-139, 1972.—In two epidemics of gastroenteritis at Clark Air Base in the Philippines, intestinal malabsorption was documented during the acute il...

Intestinal lymphoma is frequently associated with sprue-like bowel patterns. A standardized approach to the problem is suggested.Intestinal lymphoma has been subdivided into four groups, depending on the extent of involvement of the anatomical region. Only cases with specific lesions are accepted as primary lymphoma. The villous pattern in 179 cases at necropsy with suitably preserved mucosa wa...

Beginning with Gee's7 mention of atrophy of glandular crypts in 1888, many investigators of idiopathic sprue agreed that the significant changes in the small bowel at autopsy consisted of mucosal and villous atrophy, edema, and chronic mucosal inflammation and ulceration. Later, these observations were dismissed by Thaysene as due to post-mortem autolysis. According to Suarez et al.,' Koppisch ...

The intraluminal fate of orally administered radioactive vitamin B12 has been studied in control subjects with normal vitamin B12 absorption and those with vitamin B12 malabsorption due to tropical sprue. In control subjects 1 to 21% of the dose was bound to sedimentable material and 37 to 75% was bound to immunoreactive intrinsic factor. In subjects with vitamin B12 malabsorption due to tropic...

OBJECTIVE To review the experience of patients presenting with clinical manifestations of tropical sprue and assess their diagnosis and management, response to treatment and follow up. METHODS This single center retrospective descriptive study was done at Shifa International Hospital, Islamabad from January 1994 to January 2003. All patients who presented with diarrhea, anorexia, weight loss ...