Recent developments in laparoscopic gastrectomy have led to the introduction of various methods of stapled anastomosis. We have also introduced stapled anastomosis to reconstruction of the digestive tract with the aim of performing safe and quick anastomosis and enabling an early return to oral feeding. Reconstruction of the digestive tract following pancreaticoduodenectomy in our institution i...

Objectives: Bronchpleural fistula (BPF) after pneumonectomy is a serious complication, occurring in 1-15% of the cases. Study aim was to evaluate the incidence of BPFs between hand sutured and stapled bronchus closure. Methods: Hospital records of 549 consecutive pneumonectomy patients were reviewed retrospectively. The bronchial stump was closed in 510 patients using a uniform interrupted hand...

PURPOSE Trials comparing handsewn with stapled anastomoses in colon and rectal surgery have not found statistical differences. Despite this, authors have differed in their conclusions as to which technique is superior. To help determine whether differences in patient outcomes are present, a meta-analysis of all trials was performed. METHOD A meta-analysis of all randomized, controlled trials ...

HYPOTHESIS Use of circular stapled hemorrhoidectomy will result in the same or improved safety and efficacy outcomes as those of the conventional methods for hemorrhoidectomy in patients with hemorrhoids. DATA SOURCES Studies on stapled hemorrhoidectomy were identified using PREMEDLINE and MEDLINE (June 1966-June 2001), EMBASE (January 1980-June 2001), Current Contents (June 1993-June 2001), ...

Background: Can dicarba bridges (stapling) replace non-covalent interactions that stabilize helical conformation of neuroactive peptides? Result: A rational design, synthesis, structural and functional characterization of stapled conG analogs that target NMDA receptors is reported. Conclusion: Stapled conG analogs are potent antagonists of NMDA receptors and anticonvulsant compounds. Significan...

Gastric transposition with esophagogastric anastomosis is a common method of reconstruction after esophagectomy for cancer. The anastomosis can be fashioned using a handsewn or stapled technique. The choice of anastomotic technique is often debated but there is little evidence to support the use of one method over the other. We performed a meta-analysis of randomized controlled trials (RCTs) to...

Recurrence at the site of a stapled anastomosis is generally believed to result from the luminal implantation of viable cancer cells during stapling. We report a case in which colon cancer recurred twice at the site of a stapled anastomosis, despite povidone iodine (PVP-I) lavage consisting of an enema with 5% PVP-I solution before the operation and intraoperative lavage of the rectal remnant a...

outcomes of stapled and hand-sewn Roux-en-Y intestinal anastomoses in childhood.
 Materials Methods: At a university hospital, the records children who underwent roux-en-Y anastomosis between December 2007 2014 were reviewed. The data compared according to technique used (stapled versus hand-sewn).
 Results: A total 52 patients had undergone anastomosis. All biliary atresia or choledo...

Stapled hACE2 peptides inhibit the formation of SARS-CoV-2-hACE2 complex, providing basis for development anti-COVID-19 therapeutics.