We consider the problem of efficient simulation estimation of the density function at the tails, and the probability of large deviations for a sum of independent, identically distributed, light-tailed and non-lattice random vectors. The latter problem besides being of independent interest, also forms a building block for more complex rare event problems that arise, for instance, in queuing and ...

The aim of the present article is to update our understanding of the expression of the insulin-like growth factor binding proteins (IGFBPs), IGFBP proteases and their implication in the different processes of ovarian folliculogenesis in mammals. In the studied species, IGFs and several small-molecular weight IGFBPs (in particular IGFBP-2 and IGFBP-4) are considered, respectively, as stimulators...

Context: This paper presents the similarity approach for regression testing (SART), where a similarity-based test case selection technique is used in a model-based testing process to provide selection of test cases exercising modified parts of a specification model. Unlike other model-based regression testing techniques, SART relies on similarity analysis among test cases to identify modificati...

Recent data provide evidence for an important role of thrombocytes in lymphangiogenesis within human malignant disease. The aim of this study was to investigate the role of thrombocytes in lymphangiogenesis in human esophageal cancer. Perioperative peripheral blood platelet counts (PBPC) were evaluated retrospectively in 320 patients with esophageal cancer, comprising 184 adenocarcinomas (AC), ...

This paper extends the concept of a design hourly volume (DHV) which is derived from “ nth hour” to based on highest saturated hour. To calculate this hour at each ramp junction node, it necessary have permanent traffic counts (PTC) all ramps and main lanes. In practice, such are often not available. For cases, German Highway Capacity Manual proposes method that enables estimation DHV through s...

With the development of Steel Truss Corridor (STC) toward long-span and gentle development, human-induced vibration often causes large lateral problems time-delay effects STC, which will have a non-negligible impact on dynamic performance STC. In this paper, parametric model proposed by Piccardo is improved, nonlinear equation STC established considering longitudinal–lateral walking force coupl...

AbstractMost work on wireless communications had focused on having an antenna array at only one end of the wireless link — usually at the receiver. Seminal papers by Gerard J. Foschini and Michael J. Gans, Foschini and Emre Telatar enlarged the scope of wireless communication possibilities by showing that for the highly-scattering environment substantial capacity gains are enabled when antenna ...

B usinesses must evolve to meet the needs of their customers and an everchanging, competitive marketplace. Likewise, professional societ ies must adapt to meet the needs of their members in a dynamic environment. The IEEE Computer Society (IEEE-CS) has served its membership well over the past 65 years by providing high-quality publications, conferences, standards, technical committees, educatio...

Efficient clearance of synaptically released glutamate from the extracellular space is an absolute requirement for maintaining information processing in the central nervous system. In the cerebellum, clearance of glutamate relies on uptake by Bergmann glial cells and Purkinje cells (PCs). Uptake by PCs can be monitored by recording the synaptic transport current (STC) mediated by the PC-specifi...

The majority of processes met in the industrial practice have stochastic characteristics and eventually they embody non-linear behaviour. Traditional controllers with fixed parameters are often unsuitable for such processes because their parameters change. The changes of process parameters are caused by changes in the manufacturing process, in the nature of the input materials, fuel, machinery ...