Stem cells have prulipotency to differentiate into many types of cell lineages. Recent progress of avian biotechnology enabled us to analyze the developmental fate of the stem cells: embryonic stem cells / primordial germ cells (PGCs). The stem cells were identified in the central area of the area pellucida of the stage X blastoderms. These cells could be applied for production of germline chim...

Stem cells are cells with the ability to divide for indefinite periods and to give rise to specialized cells.  Stem cell therapy has now been emerged as an extraordinary promise to treat a wide range of diseases and conditions.  However, except blood stem cell transfer by bone marrow transplant which has been used as an standard practice for more than 50 years, nearly all of therapeutic potenti...

Stem cells are self-renewing cells that can be differentiated into other cell types. Conventional in vitro models for studying stem cells differentiation are usually preformed in two-dimensional (2D) cultures. The design of three-dimensional (3D) in vitro models which ideally are supposed to mimic the in vivo stem cells microenvironment is potentially useful for inducing stem cell derived tissu...

In the biotechnology industry today, there are many business models for project commercialization. These models range from independent vertical integration to certain forms of collaboration with pharmaceutical companies to complete acquisitions of projects by the big pharmaceutical companies. In this thesis, we wanted to study commercialization strategies of several biotechnology companies. We ...

stem cells are self-renewing and undifferentiated cell types that can be differentiate into functional cells. stem cells can be classified into two main types based on their source of origin: embryonic and adult stem cells. stem cells also classified based on the range of differentiation potentials into totipotent, pluripotent, multipotent, and unipotent. multipotent stem cells have the ability...

hydroxymethylglutaryl co-enzyme a reductase inhibitors, also known as statins, are a class of anti-hyperlipidemic agents. these drugs have been employed vastly to reduce the morbidity and mortality of cardiovascular disorders. soon after their introduction, benefits other than their primary actions were discovered. along with these pleiotropic properties, a series of mainly favorable effects ha...

background: this study explored the state of hematopoietic stem cell transplantation (hsct) recipient patients and problems experienced by them and nurse about these state and problems, in iran. methods: qualitative content analysis was used for analyzing semi-structured interviews with 12 hsct recipient patients and 18 nurses. results: three main categories described the hsct state and problem...

stem cell therapy could have great potential for the treatment of a wide variety of diseases. stem cells might have the ability to differentiate into a widespread cell types, and to repopulate and revitalize the damaged cells with healthy tissue, and improve its performance. we provide here the evidence supporting the critical use of stem cell as a treatment in disease conditions existing with ...

objectives : this study sought to assess the effect of low-level laser (lll) on pain and trismus after impacted mandibular third molar surgery. materials and methods : this double blind controlled clinical trial was conducted on 40 healthy patients with no underlying disease and impacted mesioangular mandibular third molars with the same level of difficulty. the patients were divided into two g...

hematopoietic stem cell transplantation (hsct) has been practiced for more than 30 years. hematological malignanciesare the main indications for this treatment. however, its indications in adults are different from children.advances in chemotherapy and target therapy have improved treatment outcome of some of the very high riskcancers, and changed indications of hsct in children. multi-center c...