Stereology has been earlier defined by Wiebel (1970) to be: “a body of mathematical methods relating to three dimensional parameters defining the structure from two dimensional measurements obtainable on sections of the structure.” SHTEREOM I is a simple windows-based software for stereological estimation. In this first part, we describe the implementation of the number and volume estimation to...

The afferent synapse between the auditory nerve fiber and the inner hair cell (IHC) represents a critical junction for hearing. Elucidation of the structure at this site will help establish the substrate for normal sound encoding as well as pathologic processes associated with hearing dysfunction. Previous applications of unbiased (design-based) stereological principles have expanded our knowle...

PURPOSE To analyze the interaction between the cellulose exopolysaccharide (CEC) and urethral tissue when used as a pubovaginal sling. MATERIALS AND METHODS Forty Wistar rats were divided into four groups. In groups A and B the cellulose exopolysaccharide (CEC) was implanted around the urethral tissue (bladder neck below the upper margin) and the rats were sacrificed at 30 and 90 days. Simila...

objective: to determine the effects of topical administration of 20% oltipraz solution on histomorphometrical and stereological aspects of skin tissue in full thickness skin wounds in laboratory rats. methods: thirty-six male wistar portion rats (220±20 g) were randomly divided into three groups (n=12). on the first day of experimentation, a 1-cm 2 circular wound was made on the posterior surfa...

CONTEXT Number of the beta cells as well as their volume is a fundamental variable in the pancreatic research. OBJECTIVES This study describes a simple method for stereological estimation of the volume of the pancreas, the total volume of the islets, and the total number, as well as the mean volume, of the beta cells in rat. METHODS The primary volume of the pancreas was measured using the ...

In this paper, we take advantage of the reconstruction properties sampling Kantorovich (SK) algorithm to estimate volume human brain for quantification Alzheimer's biomarkers. At first, goodness reconstructions is evaluated, comparing it different interpolation methods by means Peak Signal Noise Ratio (PSNR) index; then stereological Cavalieri/Point-counting technique used infer volumetric data...

The latest developments in computer-based stereology build upon the similarities of classical stereology and computer microscopy to provide refined and effective spatial analyses that also permit mapping of anatomical regions. Classical stereology and computer microscopy have developed along independent pathways as methodologies to provide a quantitative understanding of the structure of the br...