Methylphosphonate synthase is a non-heme iron-dependent oxygenase that converts 2-hydroxyethylphosphonate (2-HEP) to methylphosphonate. On the basis of experiments with two enantiomers of a substrate analog, 2-hydroxypropylphosphonate, catalysis is proposed to commence with stereospecific abstraction of the pro-S hydrogen on C2 of the substrate. Experiments with isotopologues of 2-HEP indicate ...

(E)-3-(2,6-difluorophenyl)-1-(4-methoxyphenyl)prop-2-en-1-one (1) was synthesized and characterized by 1H 13C NMR, mass spectrometry, single-crystal X-ray diffraction. Photolysis (λirr = 300 nm) of chalcone 1 in the crystalline solid state resulted stereospecific formation syn-head-to-head photodimer (β-truxinic).

A method is presented for the analysis of the fatty acid compositions in each of the three positions of a triglyceride. Diglycerides are obtained from the triglyceride by lipolysis with pancreatic lipase, and converted to a mixture of Dand L-phosphatidyl phenol. The L-phosphatide is then hydrolyzed by phospholipase A, leaving a lysophosphatide with the fatty acid in position 1, free fatty acid ...

atom transfer radical polymerization (atrp) of styrene was carried out at 105°c and a monte carlo simulation was employed to model the system. the variations of monomer conversion, the initiator concentration, average molecular weight, and molecular weight distribution were evaluated as the reaction proceeded. according to the results obtained, for similar reaction time, monomer conversion is h...

Enynes undergo stereoselective syn intramolecular bromoetherification; the stereochemical course of the reaction was elucidated by X-ray crystallographic studies and by stereospecific synthesis of authentic bromoallenes.

Stereospecific formation of spirodioxolanes has been observed on electron transfer induced ring opening of α-epoxyketones by 2,4,6-triphenylpyrylium tetrafluoroborate in the presence of cyclohexanone.

The highly regioselective, stereospecific ring-opening of trisubstituted N-tosylaziridines possessing vinyl and hydroxymethyl groups by sulfone- and sulfide-stablised carbanions is reported.