Since the dose delivery pattern in high-precision radiotherapy is different from that in conventional radiation, radiobiological assessment of the physical dose used in stereotactic irradiation and intensity-modulated radiotherapy has become necessary. In these treatments, the daily dose is usually given intermittently over a time longer than that used in conventional radiotherapy. During prolo...

conclusions ma is nowadays the most accurate stereotactic anatomic guide for targeting the human na. it is a representative example of how stereotactic microanatomy could serve the development of stereotactic microneurosurgery. following the currently used trajectory through the alic, a dbs electrode placement within the na, targeting the ma, is feasible, allowing either na or alic stimulation....

Stereotactic radiosurgery is being increasingly used for the treatment of both benign and malignant disorders such as brain metastasis, spinal cord tumors, intracranial blood vessel abnormalities and neurological/functional problems such as Parkinson’s disease, epilepsy, obsessive-compulsive disorder and trigeminal neuralgia. The purpose of this report was to present our experience at the Depar...

Background: Radiosurgery is a focal brain irradiation technique that delivers, usually in a single session, high dose of ionizing radiation. The presence of lateral electronic disequilibrium and steep dose gradients in small fields demands special attention to the selection of a suitable detector with respect to its size, composition and response. Materials and Methods : Small circular fields w...

Radiotherapy has had important role in the palliation of NSCLC. Randomized trials tend to suggest that, in general, short regimens give similar palliation and toxicity compared to longer regimens. The benefit of combining chemotherapy to radiosensitize the palliative radiation treatment is an open question, but so far it has not been proved to be very useful in NSCLC. The addition of molecular ...

Stereotactic body radiation therapy (SBRT) offers a promising opportunity for cure and/or palliation to patients with recurrent head and neck cancer whose comorbidities, performance status, and history of prior treatment may preclude many other salvage options. Stereotactic body radiation therapy appears to have a favorable response and toxicity profile compared with other nonoperative salvage ...

OBJECTIVE To investigate the outcome of linac-based fractionated stereotactic radiotherapy over the last 10 years for intracranial skull base benign meningiomas in patients who were inoperable, who had residual tumors with some components of high mitotic index after surgery and who experienced relapse of the tumor. METHODS Twenty-seven patients with intracranial skull base benign meningiomas ...

Metastatic vertebral column tumors are found in up to 20% of cancer patients, and of these, a percentage will go on to develop compression of eloquent neurological structures. Neurosurgeons often encounter these patients in an emergent situation, and decisions regarding care must be made in an expedient manner. However, many treatment paradigms depend on the histology of the causative lesion. O...