OBJECTIVE To evaluate the efficacy and toxicities of stereotactic radiotherapy for unresectable hepatocellular carcinoma. DESIGN Retrospective study. SETTING Prince of Wales Hospital, Hong Kong. MAIN OUTCOME MEASURES Treatment outcome and toxicities. PATIENTS During the period of 2000 to 2004, 16 patients with hepatocellular carcinoma treated with stereotactic radiotherapy were reviewed...

BACKGROUND To analyze the accuracy and inter-observer variability of image-guidance (IG) using 3D or 4D cone-beam CT (CBCT) technology in stereotactic body radiotherapy (SBRT) for lung tumors. MATERIALS AND METHODS Twenty-one consecutive patients treated with image-guided SBRT for primary and secondary lung tumors were basis for this study. A respiration correlated 4D-CT and planning contours...

The treatment of brainstem metastases remains a challenge as the brainstem itself is considered a neurological organ at risk. We aimed to investigate the efficacy and safety of CyberKnife hypofractionated stereotactic radiotherapy (HFSRT) for brainstem metastases, and to examine the balance between efficacy and safety for the management of neurological symptoms. A total of 26 lesions [pons (n =...

Background: Cerebral arteriovenous malformations (AVMs) are vascular lesions that may be associated with a significant morbidity and mortality. There is still today no consensus regarding treatment of unruptured AVMs. Using known data from the literature, and data from our own institution concerning stereotactic radiotherapy, our aim was to construct an equation that may be used to evaluate the...

Historically radiotherapy has always played a limited role for the treatment of HCC due to the low tolerance of the liver and the subsequent risk of radiation induced liver disease (RILD). Technologist advancements in radiation planning and treatment delivery such as Stereotactic Body Radiotherapy (SBRT) combined with Image Guided Radiotherapy (IGRT) has allowed us to further increase tumor dos...

BACKGROUND AND PURPOSE There are concerns that radiotherapy doses delivered in a magnetic field might be distorted due to the Lorentz force deflecting secondary electrons. This study investigates this effect on lung stereotactic body radiotherapy (SBRT) treatments, conducted either with or without multileaf collimator (MLC) tumor tracking. MATERIAL AND METHODS Lung SBRT treatments with an MR-...

Song and colleagues deliver a thorough and fair review of the initial clinical investigations of a new paradigm in radiotherapy most recently called stereotactic body radiation therapy (SBRT).[1] Oncology observers may take exception with the use of the designation “new paradigm.” After all, from a tumor control point of view, skeptics might say, “radiotherapy is radiotherapy.” Recent advances ...

Acoustic neuromas present a challenging problem, with the major treatment modalities involving operative excision, stereotactic radiosurgery, observation, and fractionated stereotactic radiotherapy. The morbidity/mortality following excision may differ by patient race. To address this concern, the morbidity of acoustic neuroma excision was assessed on a nationwide level. The Nationwide Inpatien...

Stereotactic radiosurgery has emerged in recent years as a key treatment technique for a number of intracranial lesions, whether malignant or benign. In this issue of IMAJ, Attia and colleagues present a review of this treatment modality in general, as well as of their own experience [1]. The group from Sheba Medical Center is to be commended for their pioneering role in the introduction of thi...