Indonesia kaya akan keanekaragaman flora dan fauna. Data menunjukkan bahwa terdapat sekitar 30.000 spesies di hutan tropis Indonesia, 9.600 tumbuhan diketahui memiliki khasiat sebagai obat. Tumbuhan menghasilkan metabolit sekunder yang sifat berracun dapat digunakan untuk mengobati berbagai penyakit manusia salah satunya yaitu Steroid Terpenoid. Beberapa tanaman dipakai adalah biji mahoni (Swie...

in chronic granulomatous disease (cgd) patients, esophageal stricture is a rare complication and the treatment of choice is still controversial. there are few reports of successful therapy with antibiotics, corticosteroids, multiple balloon dilatations or their combination. we report a 3-three-year-old iranian boy with recurrent esophageal obstruction due to cgd. the patient transiently respond...

BACKGROUND The benefits of steroid therapy in immunoglobulin A nephropathy (IgAN) have not been established. METHODS The effect of steroids on kidney survival was retrospectively investigated in 702 patients with IgAN by multivariate analyses. RESULTS There were 295 men and 407 women. The median follow-up period was 62 months. One hundred and ninety-four patients were treated with oral ster...

BACKGROUND Glucocorticoids (GCS) remain one of the mainstay treatments in the management of ulcerative colitis (UC) but up to a third of patients will ultimately fail to respond and progress to a more severe and difficult to manage disease state. Previous clinical studies suggest that the Toll-Like Receptor 9 (TLR9) agonist DIMS0150 not only induces production of key anti-inflammatory cytokines...

INTRODUCTION Glucocorticoid (GC) therapy remains important in improving the prognosis of patients with systemic lupus erythematosus (SLE). However, some patients do not achieve an effective response with GC treatment, creating an obstacle to the remission of SLE. Identification of the underlying mechanisms responsible for steroid resistance can be significant. Macrophage migration inhibitory fa...

Sweet’s syndrome (SS) is a steroid-responsive dermatological condition characterized by fever, neutrophilia and classical tender erythematous skin rash. Pregnancy-associated SS an extremely rare clinical entity must be kept in mind while approaching case of rash pregnancy. We reported pregnancy with features characteristic histopathological neutrophilic dermatosis that had benign course, resolv...