Background—Steroid resistant asthma (SRA) represents a small subgroup of those patients who have asthma and who are diYcult to manage. Two patients with apparent SRA are described, and 12 additional cases who were admitted to the same hospital are reviewed. Methods—The subjects were selected from a tertiary hospital setting by review of all asthma patients admitted over a two year period. Subje...

This study was conducted to (1) see the histopathological distribution of different subtypes in steroid resistant nephrotic syndrome (SRNS) and (2) compare the clinical, biochemical parameters and outcome between Minimal Change Disease (MCD) with non-MCD subtypes in response to immunosuppressive therapy. A retrospective analysis was done of data on all biopsy proven children with idiopathic SRN...

OBJECTIVES Acute rejection in renal transplant is considered a risk factor for short-term and long-term allograft survival. The expected reversal rate for the first acute cellular rejection, by steroid pulse, ranges between 60% and 100%, and lack of improvement within 1 week of treatment is defined as steroid-resistant rejection. This work sought to evaluate factors that lead to steroid-resista...

Nephrotic syndrome is the most common glomerular disorder in children, and corticosteroids are the first choice of treatment. While the majority of children respond to corticosteroid therapy, a few do not enter remission after daily therapy for 1-2 months, hence showing steroid-resistance. Most of these children show focal and segmental glomerulosclerosis (FSGS) upon renal biopsy. Steroid resis...

Abstract Background Nephrotic syndrome is characterized by proteinuria, hyperlipidemia, and edema. The annual incidence of nephrotic 2–7 cases/100,000 children. Methods results present study included 32 control, steroid-sensitive cases, steroid-resistant cases aged ≤ 17 years. Serum samples were handled to check serum albumin, creatinine, calcium, total cholesterol in SSNS SRNS. Pearson’s corre...

*Corresponding Author: Ahmadali Nikibakhsh MD, Associated professor of pediatric Nephrology Mailing Address: Nephrology and Transplantation Research Center, Motahari Hospital, Urmia University of Medical Sciences, Urmia, Iran Tel: +98 151 2233011-15 Fax: +98 151 2234506 Email: [email protected] The efficacy of rituximab in treatment of childhood steroid resistant and steroid dependent nephrot...