A 10 year old boy presented to our hospital with nephrotic syndrome relapse and signs of steroid toxicity in the form of posterior capsular cataract, affection of linear growth and stage 2 hypertension, in addition to steroid induced adiposity and fungal infection of the scalp resulting in cicatricial alopecia. He was diagnosed as nephrotic syndrome 6 months back. He went into remission with st...

OBJECTIVE Most cases of idiopathic nephrotic syndrome in childhood are responsive to corticosteroids. However, there is a small group of children that demonstrate steroid resistance (steroid-resistant nephrotic syndrome; SRNS), steroid dependence, or that frequently relapse (frequent-relapse steroid-sensitive nephrotic syndrome; FR-SSNS) which are more clinically difficult to treat. Therefore, ...

BACKGROUND In children, idiopathic nephrotic syndrome (INS) is primarily treated using corticosteroids. When remission is not achieved, the coadministration of potent immunosuppressant therapy becomes imperative. Cyclosporine A (CsA) is reportedly associated with a higher incidence of remission in comparison with other immunosuppressive agents. METHODS The present study investigated the respo...

OBJECTIVE To assess the efficacy of levamisole in frequently relapsing nephrotic syndrome and steroid-dependent nephrotic syndrome. STUDY DESIGN Retrospective analysis of hospital case records. SETTING Pediatric nephrology department of a tertiary referral pediatric hospital. PARTICIPANTS 62 children with frequently relapsing nephrotic syndrome and 35 children with steroid-dependent nephr...

BACKGROUND Development of steroid dependency is one of the difficult problems in the management of children with idiopathic nephrotic syndrome, leading to increased morbidity, complications and cost of treatment. Thus, predicting early in the disease course will be useful in counseling parents and may improve treatment strategy. OBJECTIVES To determine the clinical characteristics that can pr...

background: steroid dependent (sdns) and/or frequently relapsing idiopathic nephrotic syndrome (frins) is a therapeutic problem. this study was conducted to determine the effect of levamisole in children with steroid dependent and/or frequently relapsing nephrotic syndrome. methods: in this quasi-experimental study, 43 children aged 1-14 years with steroid dependent (23 cases) and/or frequently...

Background: Nephrotic Syndrome is a common childhood illness. Major problem with this disease is frequent relapse. So, it is important to identify the children at risk for relapses to treat and further follow up. Aim &Objective: Aim of present study was to determine Spot PCR is a strong indicator of relapse in Nephrotic Syndrome. The primary objective of study was to determine the correlation b...