To examine the link between binocular vision and binocular coordination of saccades we studied subjects with convergent strabismus since childhood with mild or no amblyopia: three subjects had small squint (< 10 prism D) and preserved peripheral binocular visual function with gross stereopsis; four subjects had larger squint (18-35 prism D) and no detectable stereopsis. A standard paradigm was ...

PURPOSE Comitant strabismus is a common pediatric ophthalmic disorder with both genetic and non-genetic factors contributing to its etiology. The aim of the current study is to investigate the phenomenon of a parent-of-origin effect, genomic imprinting, as a possible mode of inheritance in comitant strabismus. METHODS We performed parametric genome-wide MOD score (model-maximized LOD score) l...

PURPOSE The aim of this study was to look for the response to strabismus images in the limbic network (amygdala, hippocampus, parahippocampus) of healthy volunteers and to compare it with their reaction to viewing normal eyes. DESIGN Prospective, observational study. PARTICIPANTS Thirty-one healthy volunteers underwent functional magnetic resonance imaging (fMRI). METHODS Functional magne...

To clarify surgical outcomes for 5 ophthalmic diseases in terms of vision-related quality of life (QOL), we sent a self-administered Visual Function Questionnaire-14 (VF-14) to patients 3 months postoperatively, and the VF-14 scores for the surgical outcome of strabismus were compared with those of patients with diabetic macular edema (DME), cataract, glaucoma, and epiretinal membrane (ERM). Te...

PURPOSE To provide reference data for the measurement of ocular alignment and of angles of strabismus with a new stationary photographic apparatus at near and at distance fixation; to verify quantitative relations between the data by comparing experimental data with theoretical predictions. METHODS Use of Purkinje I and IV Reflection Pattern Evaluation in conjunction with a new stationary pho...

OBJECTIVE To evaluate the clinical performance of the Pediatric Vision Screener (PVS) in children in a pediatric ophthalmology office setting. METHODS Seventy-seven subjects between 2 and 18 years of age received gold-standard orthoptic examinations and were classified as at risk for amblyopia if strabismus or anisometropia (>1.50 diopters) was present. Strabismus was subclassified as variabl...

BACKGROUND It has been our impression that adult patients with strabismus frequently delay surgical intervention. OBJECTIVES To determine the length of time adult patients waited before undergoing strabismus surgery and to determine the reasons why these delays occurred. DESIGN, SETTING, AND PARTICIPANTS Prospective survey of consecutive patients who delayed strabismus surgery for more than...

PURPOSE Assessing health-related quality of life in patients with strabismus is important in evaluating the clinical benefits of strabismus treatment. The purpose of this study was to translate the Adult Strabismus Quality of Life Questionnaire (AS-20) into Danish and evaluate its reliability and validity in adult patients with strabismus in Denmark. METHODS The AS-20 was translated into Dani...

Dangerous hyperkalaemia has been reported following administration of succinyleholine chloride (SCC) to patients with burns, 1,2 massive trauma, a tetanus, 4 and a variety of neuromuscular disorders. T M Recently, Tammisto, e t al., 8 reported increases in blood levels of creatine phosphokinase (CPK) following administration of succinyleholine in patients with strabismus and found them to be hi...

BACKGROUND Anomalous retinal correspondence (ARC) is a neural adaptation to eye misalignment in which non-corresponding retinal points are linked in the visual cortex to provide binocular fusion. ARC within the striate cortex would require that horizontal neurons link right-eye and left-eye ocular dominance columns (ODCs) separated by a distance in the cortex proportional to the angle of strabi...