Background 4D flow is a promising new method for assessment of aortic pathology, but is limited by signal-to-noise ratio (SNR) leading to long acquisition times. Higher field strength may prove a solution. SNR in aortic 4D flow increases at 3T versus 1.5T (Strecker et al, JMRI 2012) and further by adding a contrast agent (Bock et al, MRM 2010). This work extends this comparison to human 7 Tesla...

PURPOSE To develop a new technique to treat wide-necked side-wall aneurysms, combining the implantation of intraarterial stents with the endosaccular placement of coils. METHODS Bilateral side-wall aneurysms were surgically created on the carotid arteries of four dogs. In each animal, Guglielmi detachable coils were introduced into one of the aneurysms after implantation of a balloon-expandab...

Several student proposals for changing the current distribution system will be presented by Student Association President Tim Stout to the Faculty Council Subcommittee in a meeting tonight. Stout will then report back to the SA Curriculum Committee at Monday's meeting at 7 p.m. Discussions between the two groups will continue into next semes ter when the f acu l ty subcommittee will present a p...

Dihydromyricetin (DMY) is a health-beneficial flavanonol in the family of flavonoids, extracted from Ampelopsis grossedentata (Hand.-Mazz.) W. Wang. When investigating stability DMY Dulbecco's modified Eagle's medium (DMEM) solution at 37°C by LC-MS/MS, four nitrogenous derivatives were found except for previously known dimers, oxidized products, and ring-cleavage products DMY. Compound 1 (N-DM...

α-Amino nitriles are synthesized in a one-pot, three-component coupling of aldehydes (or ketones), aniline, and trimethylsilyl cyanide using a catalytic amount of choline chloride.2ZnCl2 as a bio Lewis acidic ionic liquid. Mild Lewis acidic characteristic of this ionic liquid allows efficient synthesis of α-amino nitriles from acid sensitive aldehydes.

A facile route has been established for the synthesis of indole-substituted (S)-tryptophans from corresponding indoles, which utilizes a chiral auxiliary-facilitated Strecker amino acid synthesis strategy. The chiral auxiliary reagents evaluated were (S)-methylbenzylamine and related derivatives. To illustrate the robustness of the method, eight optically pure (S)-tryptophan analogues were synt...

OBJECTIVE As the mortality associated with coronary artery bypass grafts has fallen, morbidity has become an increasing problem. The improvement of transluminal carotid angioplasty is enlarged to patients with asymptomatic severe carotid stenosis (> 85%) requiring coronary surgery. METHODS Between January 1993 and January 1995, 10 patients underwent percutaneous carotid angioplasty prior to c...