background sinusitis is one of the most prevalent infectious diseases among those who visit doctor, which requires antibiotic intervention. the most common types of bacteria causing this disease are streptococcus pneumonia, streptococcus pyogenes, staphylococcus aureus and pseudomonas aeroginosa. nonetheless due to dangerous side effects of chemical drugs on body and increased drug resistance o...

The diethyl ether and ethyl acetate fractions of the peel fruit Solanum incanum. (S. incanum) were analyzed using gas chromatography-mass spectrometry (GC–MS). 105 compounds identified in fraction 75 fraction. Among them, 5 by fragmentation pattern, discussed, compared with NIST database. antibacterial screening was also conducted for bothdiethyl S.incanum four pathogens, two Gram-positive bact...

Comparing the pneumonic lesions produced by this very virulent streptococcus with those caused by a mildly virulent strain of the same organism, we find that with one exception the differences between them are only of a quantitative nature and not striking. There are the same intense leucocytic exudation into the alveoli and the leucocytic infiltration of the framework of the lungs. Macroscopic...

Expression of CD11b is enhanced on neutrophils recruited to the lungs during bacterial pneumonia. To determine the role that CD11b plays in pneumonia, CD11b gene-deficient (CD11b(-/-)) mice and normal wild-type (wt) mice were intranasally infected with Streptococcus pneumoniae. CD11b(-/-) mice had an enhanced outgrowth of pneumococci in the lungs and an increased dissemination of the infection,...

BACKGROUND Day-care centre (DCC) attendees play a central role in maintaining the circulation of Streptococcus pneumoniae (pneumococcus) in the population. The prevalence of pneumococcal carriage is highest in DCC attendees but varies across countries and is found to be consistently lower in Finland than in Portugal. We compared key parameters underlying pneumococcal transmission in DCCs to und...

We describe the high-efficiency transformation of several virulent, encapsulated isolates of Streptococcus pneumoniae. Transformation was effected by the induction of competence with competence factor and was apparently the result both of inducing noncompetent recipients and overcoming the inhibition imposed by the capsule.