www.sciencemag.org (this information is current as of November 20, 2008 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/296/5573/1681 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/296/5573/1681/DC1 can be f...

In this paper, we present a unified analysis of matrix completion under general low-dimensional structural constraints induced by any norm regularization. We consider two estimators for the general problem of structured matrix completion, and provide unified upper bounds on the sample complexity and the estimation error. Our analysis relies on results from generic chaining, and we establish two...

Transient Receptor Potential (TRP) proteins are a large family of ion channels, grouped into seven sub-families. Although great advances have been made regarding the activation and modulation of TRP channel activity, detailed molecular mechanisms governing TRP channel gating are still needed. Sensitive to electric, chemical, mechanical, and thermal cues, TRP channels are tightly associated with...

The analogy of a semantic network to hypertext has long been recognized, and semantic networks have been considered as a logical model of hypertext – especially for those hypertexts with typed nodes and links. Moreover, wordnets form the most representative type of semantic networks in the field of Natural Language Processing and semantics in particular. It is obvious that hypertext and wordnet...

Multimillion-atom molecular-dynamics simulations are used to investigate the shock-induced phase transformation of solid iron. Above a critical shock strength, many small close-packed grains nucleate in the shock-compressed body-centered cubic crystal growing on a picosecond time scale to form larger, energetically favored grains. A split two-wave shock structure is observed immediately above t...

3D-mesh models are widely used to represent real objects in synthesized scenes for multimedia or cultural heritage applications, medical or military simulations, video games and so on. Indexing and analyzing these 3D data is a key issue to enable an effective usage of 3D-mesh model for designers and even for final users. The researches of our group mainly focus on these problems. In this paper,...

Nuclear receptors play an important role in transcription regulation. They bind as homoor heterodimers to the response elements of their target genes and interact with numerous and diverse partners, e. g. coactivator and corepressor proteins, and transcription factors. Many of these processes are ligand-dependent, i. e. binding of natural ligands activates the nuclear receptor through conformat...

Structures of many of the cell surface receptor-ligand complexes mediating the interactions between T cells and target cells have been determined in the past ten years. While snapshots of T cell receptors bound to their peptide-MHC ligands appear to have defined a general interaction or "docking" solution, many of the most fundamental structural questions in antigen recognition lack detailed an...

Granular materials are ubiquitous in nature and very common in industrial processes, but it is only recently that their unusual properties have begun to receive detailed attention from the physicists community [1, 2]. The earliest documented studies of granular matter date back to Faraday [3], who discovered the convective behavior of vibrated sand, and Reynolds [4], who noted that compactified...

Thanks to the development of the federated systems approach on the one hand and the emphasis on user involvement in database design on the other, the interest in schema integration techniques is significantly increasing. Theories, methods and sometime tools have been proposed. Conflict resolution is the key issue. Different perceptions by schema designers may lead to different representations. ...