BACKGROUND Due to optimal safety of sublingual immunotherapy (SLIT), it was suggested that a slow up-dosing phase maybe not necessary, and therefore the treatment will be more patient-friendly, avoiding dosing mistakes. PATIENTS Twenty adult patients suffering allergic rhinitis due to Parietaria, were enrolled. Half of them received the traditional schedule and the other half immediately star...

OBJECTIVES Sublingual immunotherapy (SLIT) is a viable alternative to subcutaneous immunotherapy to treat allergic rhinitis and asthma, and is widely used in clinical practice in many European countries. The clinical efficacy of SLIT has been established in a number of clinical trials and meta-analyses. However, because SLIT is self-administered by patients without medical supervision, the degr...

A growing body of evidence is accumulating in support of sublingual immunotherapy (SLIT) for the treatment of allergic rhinitis and asthma. Several European countries use SLIT in preference to the more established subcutaneous immunotherapy (SCIT) because of improved safety and ease of administration, particularly among children and those with asthma. However uncertainty persists, particularly ...

BACKGROUND Allergen immunotherapy (AIT) has proven to be effective. However, no biomarkers capable of predicting the clinical response to AIT have been detected. The aim of the present study was to determine a cutoff value for serum specific IgE that could be associated with effective AIT. METHODS We evaluated 174 allergic patients (83 males) with ages ranging between 6 and 77 years. All pati...

Background The aim of this non-interventional study was to document the impact of a sublingual allergen immunotherapy (AIT) with Oralair 5-grass pollen tablets (Stallergenes, France) on symptom severity, use of symptomatic medication and tolerability in patients with grass pollen-induced allergic rhinoconjunctivitis (RC) over 2 years of routine medical practice treatment. This poster focuses on...

Background: Subcutaneous injection route (SCIT) is burdened with the risk of severe adverse events; therefore, sublingual immunotherapy (SLIT) is being increasingly investigated. The efficacy of SLIT in asthma has been reviewed in a Cochrane meta-analysis. Allergic sensitization to Dermatopha-goides pteronyssinus (Dp), Dermatophagoides siboney (Ds) and Blomia tropicalis (Bt) is strongly linked ...

Many pharmacological options exist for allergic rhinitis. Intranasal corticosteroids are the most effective medication class for patients with moderate to severe symptoms; those with milder intermittent symptoms can be treated with a second-generation oral or intranasal antihistamine. Allergen avoidance measures may also be helpful. In patients whose symptoms are refractory to standard pharmaco...

Due to its excellent safety profile, ease of administration, and economic considerations, sublingual immunotherapy (SLIT) is becoming a preferred form of allergen specific immunotherapy. The efficacy of SLIT is still debated. The purpose of this act of practice trial is to evaluate quality of life outcomes in patients treated with SLIT. Fifty one patients with allergic rhinoconjunctivitis demon...

1. Review the target audience, learning objectives and author disclosures. 2. Complete the pre-test online at www.jacionline.org (click on the Online CME heading). 3. Follow the online instructions to read the full version of the article, including the clinical vignette and review components. 4. Complete the post-test. At this time, you will have earned 1.00 AMA PRA Category 1 CME Credit. 5. Ap...

Accessible online at: www.karger.com/journals/iaa The WHO has recommended sublingual immunotherapy (SLIT) as the suitable treatment for allergic rhinitis in adults [1]. Our article is based on 20 double-blind, placebo-controlled studies published in peer-reviewed international journals and our own experiences with this therapy in a controlled study with patients allergic to grass pollen [2]. Ei...