To the Editor: In the literature on Axis I comorbidity in borderline personality disorder (BPD), males with BPD invariably evidence significantly higher rates of substance use disorders than females.1–5 In a previous study, we found that the self-reported abuse of prescription medications was associated with BPD, according to 2 self-report measures for this Axis II disorder.6 However, we did no...

Conduct disorder (CD) and antisocial personality disorder (ASPD) are established risk factors for substance use disorders in both the general population and among persons with schizophrenia and other severe mental illnesses. Among clients with substance use disorders in the general population, CD and ASPD are associated with more severe problems and criminal justice involvement, but little rese...

Adolescent substance abuse is a major public health concern. It is associated with an increased incidence of various psychiatric disorders like depressive disorders, anxiety disorders, attention deficit hyperactivity disorder, and conduct disorders and the relationship between mental and behavioral disorders and the substance use problems seems to be bi-directional. Adolescent suicide and subst...

Assortative mating can exert a profound influence on the phenotypic composition of the population since it may result in an increase in the frequency of the genotypes associated with extreme phenotypes. Applied to the risk for a disorder such as substance abuse, this would mean a possibility for an increase in the risk and severity of the disorder in consecutive generations. This paper reviews ...

BACKGROUND In light of the emphasis on drug abuse, this study explored the relative prevalence of substance use disorders among United Kingdom (UK) prison inmates in the context of findings from a general inmate population in the United States (US). The lead author of the report conducted a structured diagnostic interview with 155 new admissions to one of two prisons in the UK using the CAAPE (...

Background: Prisoners are a vulnerable group within societies, and also threaten society due to their dangerous behavior. The objective of the present study was to evaluate the relationship between prisoners’ personality disorders and their crime and substance use.Methods: This was a descriptive-correlational study. The statistical population consisted of all prisoners of Kerman, Iran. Through ...

BACKGROUND Many studies have found an association between Substance Use Disorders (SUDs) and Attention Deficit Hyperactivity Disorder (ADHD) in children, adolescents and adults. We intended to determine whether substance abuse and SUDs are associated with former and current ADHD symptomatology in a non-clinical sample of 17 and 18 year old males. METHOD A representative sample of 3280 young m...

Carlos M. Grilo, Ph.D., is an associate professor in the Department of Psychiatry and director of the Eating Disorder Program; Rajita Sinha, Ph.D., is an associate professor in the Department of Psychiatry and director of the Substance Abuse Treatment Unit; and Stephanie S. O'Malley, Ph.D., is a professor in the Department of Psychiatry and director of the Division of Substance Abuse Research, ...