The use of the sulphonamides and penicillin in the therapy of pneumonia and bronchopneumonia in children has considerably altered the prognosis in these diseases. Although there are reports on the results of treatment with various sulphonamides, there are only a few published studies on the response to treatment with penicillin alone or with penicillin and sulphonamides combined. It was felt, t...

Septicaemia caused by N. flavescens is reported for the first time. The septicaemia developed following dental surgery, and the clinical picture was indistinguishable from that of chronic meningococcaemia. The skin lesions resembled the cutaneous manifestations of gonococcaemia. The patient responded to treatment with sulphonamides and penicillin with no relapse over 18 months of follow-up.

This is a concise account of the clinical uses of sulphonamides, penicillin and other antibiotics. The first eight chapters describe the drugs, their pharmacology, toxicity, administration and dosage, and the next fourteen chapters deal with their uses in various diseases. The information is well arranged for easy reference. The author lays emphasis on bacteriological diagnosis as a guide to tr...

Interesting synergism in vitro between a recently introduced antibiotic, colistin methane sulphonate, and sulphonamide drugs is described. The observations were extended to polymyxin B sulphate and sulphonamides with essentially similar results. The combinations are bactericidal at therapeutic levels, the ratio of drugs to one another is not critical, and the effect is present over a fairly wid...