Porous silicon has found increased attention as a drug delivery system due to its unique features such high payloads, surface area and biodegradation. In this study supercritical fluid (SCF) assisted drying of ultrahigh porosity (>90%) particles flakes was shown result in much higher mesopore volumes (~4.66 cm3/g) areas (~680 m2/g) than with air-drying. The loading physical state the model (S)-...

Activated carbon fiber/carbon aerogel (ACF/CA) composites were fabricated by gelling a mixture of ACF and resorcinol and furfural, followed by supercritical drying of the mixture in isopropanol. The product then went through carbonization in a nitrogen atmosphere. The fabrication conditions, such as the mass content of R–F, the content of the ACF added, and the gelation temperature, were explor...

A comprehensive study of release kinetics a hydrophilic drug from bio-aerogels based on pectin was performed. Pectin aerogels were made by polymer dissolution, gelation (in some cases this step omitted), solvent exchange and drying with supercritical CO2. Theophylline loaded its studied in the simulated gastric fluid during 1 h followed intestinal fluid. concentration, initial solution pH conce...

   Small changes in pressure or temperature, close to the critical point, lead to large changes in solubility of supercritical carbon dioxide (CO2). Environmentally friendly supercritical CO2 is the most popular and inexpensive solvent which has been used for preparation of nanodrugs and nanocarriers in drug delivery system with supercritical fluid technology. Delivery...

Supercritical fluid technology is a rapidly expanding analytical technique. Here we give a brief insight into the background of supercritical fluid technology and how supercritical fluid extraction and supercritical fluid chromatography work in analysis. The applications of these two techniques in forensic science are known to be important. The main area of forensic use of supercritical fluid t...

Food-grade porous materials, aerogels and so-called cryogels, were prepared from cellulose hydrogels obtained solutions at increasing concentration (3, 4, 5%, w/w) by supercritical-CO2-drying (SCD) freeze-drying (FD), respectively. The structure depended on the applied drying technique, with showing a denser network pores <200 nm in diameter, specific surface area of 370–380 m2g-1, porosity 92–...

dissolution pressure and nozzle temperature effects on particle size and distribution were investigated for ress (rapid expansion of supercritical solution) process. supercritical co2 was used as solvent and ibuprofen was applied as the model component in all runs. the resulting ibuprofen nano-particles (about 50 nm in optimized runs) were analyzed by sem and laser diffraction particle size ana...

supercritical fluid extraction (scfe) is a soil remediation technology. at present, only a few companies are using from this method, all of which are technical based on conventional methods of extraction such as soilex solvent extraction. because of the hard enforcement of environmental conservation law, using green technology seems imperative. this paper endeavors to carry out the feasibility ...