Direct and indirect immunofluorescent studies of sural nerves were carried out in two patients with paraproteinaemia and neuropathy, in four other patients with axonal or demyelinating neuropathies, and in one normal sural nerve. IgM was demonstrated directly in the two cases of paraproteinaemia and neuropathy, and indirectly, using the serum of one of these cases, in a case of axonal neuropath...

A 33-year-old man with acute myelogenous leukemia developed a rapidly progressive painful neuropathy with symmetric sensorimotor and autonomic deficits 7 weeks after chemotherapy. Nerve conduction studies showed axonal sensorimotor neuropathy. Because of the rapidly progressive course, a sural nerve biopsy was performed, which showed intraneural leukemic infiltrates (figure). This case illustra...

Single unit potentials were recorded from sural and medial gastrocnemius nerves. Action potential amplitude, integrated area and half-width (duration) were approximately proportional to conduction velocity, raised to the powers 1.5, 1 and -0.5 respectively with the sural nerve, and 2, 1.5 and -0.5 for the medial gastrocnemius nerve. These empirical relationships were applied to the computation ...

Sural nerve regeneration and sensation were evaluated in 16 subjects five or more years after fascicular or whole nerve biopsy. Conduction studies demonstrated successful nerve regeneration in all subjects who had whole nerve biopsy. Postbiopsy interrogation revealed no long-term pain or paresthesias but a high incidence of tactile-induced dysesthesias. No significant difference was seen when a...

A 59-year-old woman with a long-standing diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) developed facial numbness and exophthalmos. Sural nerve biopsy revealed onion bulb formation consistent with CIDP. Neurologic examinations revealed distal dominant muscle atrophy with areflexia and impairment of all sensory modalities; cranial nerve involvement, including bilat...

There are numerous perforator flaps reported in the literature for head and neck reconstruction. We are presenting a case report of squamous cell carcinoma of Tongue which was operated by hemi glossectomy, modified radical neck dissection and reconstruction was done with medial sural artery perforator flap (MSAP). Preoperatively handheld Doppler was used to identify the perforator. The size of ...