BACKGROUND/AIMS Phagocytosis depends on the formation of engulfment pseudopodia surrounding the target. We tested in microglia, monocyte-derived cells in the brain, whether a swelling-activated Cl(-)-current (I(Cl,swell)), required for global cell volume (CV) regulation, also contributes to local expansion and retraction of engulfment pseudopodia. METHODS We used scanning electron microscopy ...

S U M M A R Y The Cape Verde mid-plate swell is the largest amplitude oceanic mid-plate swell on Earth at ∼1800 km in diameter, with a crest ∼2.2 km high, and long-wavelength positive geoid, gravity and heat flow anomalies of 8 m, 30 mGal and 10–15 mW m−2, respectively. These characteristics and its location on the slow moving-to-stationary African Plate, which concentrates the volcanism and as...

Abstract With the continuous development of dredging business to overseas markets, ships are faced with a more and complex hydrodynamic environment. Swell long wave periods has great impact on adaptability ship operations. Focused Trailing Suction Hopper Dredger (TSHD), this paper studied motion response characteristics TSHD under influence swell. The result shows that is severely affected by a...

We present a new resource for Swedish, SweLL, a corpus of Swedish Learner essays linked to learners’ performance according to the Common European Framework of Reference (CEFR). SweLL consists of three subcorpora – SpIn, SW1203 and Tisus, collected from three different educational establishments. The common metadata for all subcorpora includes age, gender, native languages, time of residence in ...

Neuroendocrine (NE) differentiation of prostate epithelial/basal cells is a hallmark of advanced, androgen-independent prostate cancer, for which there is no successful therapy. Here we report for the first time on alterations in regulatory volume decrease (RVD) and its key determinant, swelling-activated Cl- current (I(Cl,swell)), associated with NE differentiation of androgen-dependent LNCaP ...

This work presents the development of a weakly compressible smoothed particle hydrodynamics (WCSPH) model for simulating two-dimensional transient viscoelastic free surface flow which has extensive applications in polymer processing industries. As an illustration for the capability of the model, the extrudate or die swell behaviors of second-order and Olyroyd-B polymeric fluids are studied. A s...

e have been studying the phenomenon of thickness swell in woodbased composites as part of our overall research program to address composite product manufacture and performance (Xu and Winistorfer 1995a, 1995b; Wang and Winistorfer 2000a, 2001). We purport that one of the key variables in understanding the thickness swell phenomenon is recognition of the density profile through the panel thickne...

The objective of this study was to investigate the effects of hot water extraction process on the dimensional stability of oriented strand composites. Aspen wood strands were extracted using various severity factor levels. Phenol formaldehyde and polymethylene diphenyl diisocyanate resins were used for production of the oriented strandboard panels. Six panel groups were produced from the extrac...

Guanosine 5'-O-(3-thiotriphosphate) (GTPgammaS) activated the I(Cl,swell) anion channel in N1E115 neuroblastoma cells in a swelling-independent manner. GTPgammaS-induced current was unaffected by ATP removal and broadly selective tyrosine kinase inhibitors, demonstrating that phosphorylation events do not regulate G protein-dependent channel activation. Pertussis toxin had no effect on GTPgamma...

BACKGROUND ICln is a multifunctional protein involved in the generation of chloride currents activated during regulatory volume decrease (RVD) after cell swelling (ICl(swell)). Growth factor receptors play a key role in different cellular processes and epidermal growth factor (EGF) regulates swelling-activated chloride permeability. AIM We set out to investigate if the EGF-induced upregulatio...