Zinc oxide (ZnO) nanoparticles have received growing attention for several biomedical applications. Nanoparticles proposed for these applications possess the potential to interact with biological components such as the blood, cells/ tissues following their administration into the body. Hence we carried out in vivo investigations in Swiss Albino Mice to understand the interaction of ZnO nanorods...

Background: Recently, we reported immunological and hematological perturbations in Swiss albino mice exposed to clomazone (CMZ) (Nassef, The Egyptian Journal of Experimental Biology (Zoology) 13(1):91–101, 2017). Aim: To continue searching immunological perturbations of CMZ, the main goal of the current study was to investigate the probable immunobiochemical perturbations caused by CMZ and to e...

Acute toxicity study of potassium permanganate was carried out in Swiss albino mice. Potassium permanganate was administered at dose rate of 0.0, 500, 1000, 1500, 2000, 2500, 3000 and 3500mg/kg body weight to groups 1, 2, 3, 4, 5, 6, 7 and 8, ten per group for LD50 determination. The dead animals were posted for gross lesions. A predetermined dose of 160mg/kg of the chemical was administered to...

Worldwide application of pesticides is increasing continually to the extent that they have become an integral part of the ecosystem. Approximately 5.6 billion pounds of active pesticide ingredients are used annually throughout the world (USEPA, 2001). Post market surveillance has revealed that as many as 25 million agricultural workers worldwide experience unintentional pesticide poisoning each...

Introduction: Depression disorder has significant potential morbidity and mortality, contributing to suicide, incidence adverse outcomes of medical illness, disruption in interpersonal relationships, substance abuse, lost work time. Objectives: The present study was designed the anti-depressant activity seeds extract Zanthoxylum armatum using a forced swim test tail suspension on Swiss albino m...

*Corresponding author: Dr. Jaimala sharma, Department of Zoology, University of Rajasthan, Jaipur-302055, India. E-mail: [email protected] Background: Radiotherapy is the main modality of cancer treatment. There are many chemical radioprotectors which unfortunately have lethal or toxic effect. Therefore the search is on to find out natural plant based radioprotectors. A well known medi...

The antitumor activity of ethanol extract of Prosopis glandulosa Torr. (EPG) was evaluated against Ehrlich ascites carcinoma (EAC) tumor model in Swiss albino mice on dose dependent manner. The activity was assessed using survival time, average increase in body weight, hematological parameters and solid tumor volume. Oral administration of EPG at the dose of 100, 200 and 400 mg/Kg, significantl...