objective(s):leptin receptor (lepr) is a member of the class i cytokine receptor super-family that is known implicated in the initiation and progression of breast cancer. we have investigated the effect of q223r polymorphism on the breast cancer susceptibly in a sample of iranian subjects. materials and methods:we utilized a polymerase chain reaction (pcr) restriction fragment length polymorphi...

background post-mastectomy breast reconstruction is commonly performed in the united states with numerous options available to patients and providers. this study evaluated patient race and provider in prediction of patient satisfaction following post-mastectomy breast reconstruction. methods the patient satisfaction for women who underwent post mastectomy breast reconstruction at university of ...

BACKGROUND Patients which have diagnosed with a cancer, have a life time risk for developing another de novo malignancy depending on various inherited, environmental and iatrogenic risk factors. Cancer victims could survive longer due to settling treatment modalities, and then would likely develop a new metachronous malignancy.This article aims to report our observed trend of increasing, in pre...

background: brca1 and brca2 genes have been recognized to be responsible for 20-30% of hereditary breast can­cers and approximately 50% of familial breast and ovarian cancers. therefore, the demand for brca1 and brca2 muta­tion screening is rapidly increasing as their identification will affect medical management of people at increased risk. because of high costs involved in analysis of brca1 a...

SUMMARY: BACKGROUND: Metastases to the parotid and thyroid glands from breast cancer are rare and have a poor prognosis. CASE REPORT: We present the case of a patient with breast carcinoma and synchronous involvement of both the parotid and thyroid gland, and review the literature on this subject. CONCLUSION: Metastatic malignancy in clinically suspect thyroid and parotid nodules could be detec...

We report a case of synchronous bilateral breast cancer with ductal and medullary carcinoma. A 60-year-old woman presented with lesion in both breasts which were mammographically found two years ago. Ultrasonography proved two suspected masses in breasts. Fine needle cytology was performed and confirmed bilateral carcinoma but with different cytological findings. The cytological feature of the ...

introduction: the adaptive neuro-fuzzy inference system (anfis) is a soft computing model based on neural network precision and fuzzy decision-making advantages, which can highly facilitate diagnostic modeling. in this study we used this model in breast cancer detection. methodology: a set of 1,508 records on cancerous and non-cancerous participant’s risk factors was used.  first, the risk fact...