www.ondrugdelivery.com 27 In this article, Mahesh Chaubal, PhD, Senior Director, Drug Development, R&D Medical Products, Baxter Healthcare Corporation, provides a glimpse of some of the challenges faced during the development of viscous formulations of biopharmaceutical products for injection, from a formulator’s perspective, especially when the finished product is filled in a prefilled syringe...

OBJECTIVES This study investigated the sharing of drug preparation equipment as a possible route of hepatitis C virus (HCV) transmission. METHODS HCV seroconversion was measured in a cohort of 317 injection drug users who tested negative for HCV antibody at recruitment. RESULTS Cumulative HCV incidence was 16.7% per year. Among those who did not share syringes, HCV seroconversion was associ...

A double cannula is described suitable for the aspiration of soft lens matter. The cannula is a modification of a double irrigation needle already marketed and will be available in a presterilised disposable pack for use with disposable syringes.

and Bricon. Translated from the Second Edition, with Additions by Andrew S. Currie, M.D. London: H. K. Lewis. 1887. Dr. Currie has done good service in giving us a translation of this book, as it is most desirable that English readers should be made familiar with foreign works, that have been well received in their own country. There is first a most meagre history of the hypodermic method and a...

more, syringes cannot be sterilized assembled or lubricated, and the syringe containers, whether multiple or single, must be so constructed that steam can freely penetrate to all surfaces of the syringe (Stewart, 1957; Darmady and Hughes, 1955). After sterilization a separate process is necessary to seal the containers before distribution to the user. Although syringes in their containers can b...

OBJECTIVE To describe the injection and sharp waste disposal practices of general practitioners of Murree, Pakistan. METHODOLOGY In-depth interviews of all general practitioners available between 10th to 20th July 2000 were conducted. Practitioners were interviewed about injection administration and disposal of waste due to injections and other sharp material. RESULTS Twenty general practit...