purpose: to evaluate the results of combined chemotherapy and periocular carboplatin injection to control advanced intraocular retinoblastoma (rb). methods: in this prospective interventional case-series, we included 8 eyes of 8 patients with advanced intraocular rb (group c or d in international intraocular retinoblastoma classification, iirc). in these patients, periocular carboplatin was inj...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: to determine the prevalence of cryoglobulins in iranian patients with systemic lupus erythematosus (sle) and evaluate the correlation of cryoglobulins with disease activity in these patients. materials and methods: in a cross-sectional study, we investigated 80 consecutive women who fulfilled the 1982 revised c...

conclusions this report aimed to increase awareness of the occurrence of extra-intestinal systemic manifestations of rotavirus infection. although such cases may be rare, they still suggest that that rotavirus is a systemic viral infection. case presentations we report three pediatric cases of rotavirus infection: one accompanied by encephalopathy and two with elevated hepatic transaminase acti...

this study explored nominalized expression types in an applied linguistics book and a biology book as 2 distinct disciplines. the books were carefully read, the nominalized expression types were identified, the frequencies of the nominalization types were counted, and eventually chi-square was administered. results revealed no significant difference in using nominalization. furthermore, the den...

Poor water solubility for many drugs and drug candidates remains a major obstacle to their development and clinical application. Conventional formulations to improve solubility suffer from low bioavailability and poor pharmacokinetics, with some carriers rendering systemic toxicities (e.g. Cremophor(®) EL). In this review, several major nanonization techniques that seek to overcome these limita...

Clinical trials of intralymphatic immunotherapy (ILIT) have been performed to overcome the limitations of long-term therapy and the local or systemic hypersensitivity reactions in conventional allergen-specific immunotherapy, including subcutaneous or sublingual immunotherapy. Additionally, several animal studies of ILIT have been conducted in the form of translational or veterinary research. W...

 Overall, taking account of both coverage and formula effect differences and within the limitations of how price data is collected within the UK, the Retail Prices Index (RPI) is as good a consumer price index as one can get for uprating purposes. The systemic difference between the RPI and the Consumer Prices Index (CPI), currently (2015) running at 1.0 percentage points per annum, results pr...

Primary Sjögren's syndrome (pSS) is a complex autoimmune disease characterised by local exocrine glandular involvement and systemic multiorgan manifestations. In this review we will discuss the value of the histological examination of the salivary glands in the classification criteria, and more recently as prognostic tool for patient stratification and monitoring. The limitations of the current...

introduction : as the result of epidemiological transition and aging of iranian population, the frequencies of systemic diseases among patients in of need endodontic treatment has increased, especially within developed cities. however, there have been no concise reports of systemic diseases in iranian patients. based on this need, the present investigation was conducted to assess the frequency ...