Family data and rare variants are two key features of whole genome sequencing analysis for hunting the missing heritability of common human diseases. Recently, Zhu and Xiong proposed the generalized T(2) tests that combine rare variant analysis and family data analysis. In similar fashion, we developed the extended T(2) tests for longitudinal whole genome sequencing data for family-based associ...

We consider a bivariate process Xt = (X t , X t ), which is observed on a finite time interval [0, T ], at discrete times 0, ∆n, 2∆n, · · ·. Assuming that its two components X and X have jumps on [0, T ], we derive tests to decide whether they have at least one jump occurring at the same time (“common jumps”) or not (“disjoint jumps”). There are two different tests, for the two possible null hy...

INTRODUCTION This study investigated the validity of two brief cognitive tests (Memory Alteration Test [M@T] and Test Your Memory [TYM] test) for identifying people with aMCI in the community. METHODS Older people were invited to participate by their general practitioner practice. Eligible participants were assessed for aMCI using an operationalized approach to the Petersen criteria and the M...

Learning a hidden hypergraph is a natural generalization of the classical group testing problem that consists in detecting unknown hypergraph Hun = H(V, E) by carrying out edge-detecting tests. In the given paper we focus our attention only on a specific family F(t, s, `) of localized hypergraphs for which the total number of vertices |V | = t, the number of edges |E| 6 s, s ¿ t, and the cardin...

Likert-type item is the most popular response format for collecting data in social, educational, and psychological studies through scales or questionnaires. However, there no consensus on whether parametric non-parametric tests should be preferred when analyzing data. This study examined statistical power of each was analyzed independently survey studies. The main purpose to examine Wilcoxon-Ma...

In clinical research, comparisons of the results from experimental and control groups are often encountered. The two-sample t-test (also called independent samples t-test) and the paired t-test are probably the most widely used tests in statistics for the comparison of mean values between two samples. However, confusion exists with regard to the use of the two test methods, resulting in their i...

Graphical and numerical illustrations of the effects of moderate to severe rounding of normal data on the values of test statistics, actual significance level, and power for one-sample t tests and paired t tests. Goodness-of-fit tests confirm that rounded normal data are not normal. Combinatorial computations, simulations, and graphs are made using R. The level of programming, exposition, and s...

Residual stresses induced by the welding processes may, in some cases, result significant warping and distortions that can endanger integrity of welded structures. This document reports an investigation process to make a dissimilar T-joint through advanced Finite Element (FE) modelling dedicated laboratory test. The consisted two plates materials, AISI304 S275JR steels, both having thickness 5 ...

We exhibit intrinsic definitions of inequality tests, sorting functions and comparators as isomorphic presentations of total preorders (orders): • Inequality tests are functions of type T × T → Bool that are reflexive, transitive and total. • Sorting functions are functions of type T ∗ → T ∗ (mapping finite sequences of elements of type T ) that permute their input and do so consistently for ea...