Mobile applications, commonly known as apps, have become a significant line of business for IS commerce. There is an App for that! With this slogan Apple suggests that there is app out there for many uses and indeed for every circumstance within our everyday life. However, there is a lack of knowledge of what business models prevail in successfully developing and capitalizing an app. This paper...

The Amyloid Precursor Protein (APP) undergoes sequential proteolytic cleavages through the action of beta- and gamma-secretase, which result in the generation of toxic beta-amyloid (Abeta) peptides and a C-terminal fragment consisting of the intracellular domain of APP (AICD). Mutations leading to increased APP levels or alterations in APP cleavage cause familial Alzheimer's disease (AD). Thus,...

Among several traditional and novel mobile app recommender techniques that utilize a diverse set of app-related features (such as an app’s Twitter followers, various version instances, etc.), which apprelated features are the most important indicators for app recommendation? In this paper, we develop a hybrid app recommender framework that integrates a variety of app-related features and recomm...

Endocytosis of amyloid-β precursor protein (APP) is thought to represent the major source of substrate for the production of the amyloidogenic Aβ peptide by the β-secretase BACE1. The irreversible nature of proteolytic cleavage implies the existence of an efficient replenishment route for APP from its sites of synthesis to the cell surface. We recently found that APP exits the trans-Golgi netwo...

The objectives of this study were to describe the effects of an alternate payment plan (APP) on clinical surgical practice--at eight surgical divisions of Children's Hospital of Eastern Ontario--and to emphasize the important role of corporate indicators (CIs). To do this, we analyzed CIs comparing two years before the implementation of the APP with years one and two and years three and four po...

The efforts were made in the present study to seek two objectives: determining the effect of Telegram as a social network on second language achievement of Iranian foreign language (EFL) learners, and exploring the EFL learner’ attitude toward using Telegram for language learning purposes. To this end, 40 EFL learners were randomly selected and then divided into two groups of experimental and c...

Against the backdrop of new attention economy (Giraldo-Luque & Fernández Rovira, 2020), which is based on attracting audience interest, this research analyses production and distribution media content through emerging Telegram platform. Attracting has become main objective in digital environment. To achieve aim, more personalised now being produced, attempts are made to reach user a direct ...

Dieser Beitrag untersucht normalisierende Strategien extrem rechter Influencer*innen in der Corona-Pandemie auf Telegram. Anlass hierfür ist die sogenannte Querdenken-Bewegung, Milieus von Impfgegner*innen über Esoteriker*innen bis hin zur extremen Rechten vereint und sich maßgeblich Telegram informiert organisiert. Im Digitalen Straße wird deutlich, dass den Diskursen Bewegung rechtes Gedanken...