A general simulation procedure is described to validate model fitting algorithms for complex likelihood functions that are utilized in periodic cancer screening trials. Although screening programs have existed for a few decades, there are still many unsolved problems, such as how age or hormone affects the screening sensitivity, the sojourn time in the preclinical state, and the transition prob...

Temperatures in the Arctic have increased by an astounding 1 °C in response to anthropogenic forcing over the past 20 years and are expected to rise further in the coming decades. The Pliocene (2.6–5.3 Ma) is of particular interest as an analog for future warming because global temperatures were signifi cantly warmer than today for a sustained period of time, with continental confi gurations si...

chloritoid is crystallised with chlorite, white mica and garnet in chlorite zone metapelites ofthe regional metamorphic rocks of the sanandaj-sirjan metamorphic belt in southern iran. chemistry ofcoexisting minerals is studied using microprobe analysis. application of the chlorite-chloritoidgeothermometry gives temperatures of 515°c and 557°c. the chlorite-garnet fe-mg exchangegeothermometer in...

Bovine viral diarrhea disease is one of the viral diseases in cattle that were reported 10-90 percent in many countries. The causative RNA virus is a member of the family Flaviviridae and the genus pestivirus which is antigenically closely related with the virus of BD in sheep. Cattle are the most sensitive species to virus and are considered the principal reservoir of BVD viruses. A large prop...

Background and aim Postpartum period is associated with significant changes in the quality of women's lives. These changes can affect the health of both the mother and child. Given the importance of the postpartum period and the factors influencing quality of life after childbirth especially the method of childbirth, the aim of this study was to determine the relationship between quality of lif...

Photoluminescence (PL) is investigated as a function of the excitation intensity and temperature for lattice-matched InGaAs/InAlAs quantum well (QW) structures with well thicknesses of 7 and 15 nm, respectively. At low temperature, interface fluctuations result in the 7-nm QW PL exhibiting a blueshift of 15 meV, a narrowing of the linewidth (full width at half maximum, FWHM) from 20.3 to 10 meV...

bouin- miandasht granitoid pluton (bmgp), which outcropped to the north of bouin-miandasht- aligoudarz road, was emplaced into low to medium grade of triassic to early jurassic metapelitic rocks of sanandaj-sirjan structural zone. in this study we do provide the first investigations of bmgp by means of anisotropy of magnetic susceptibility (ams). most km values for the main felsic compositions ...