نتایج جستجو برای: temperature sensitive hemagglutinin tsh

تعداد نتایج: 730518  

2013
Dabuswinee Sukkhojaiwaratkul Pat Mahachoklertwattana Preamrudee Poomthavorn

Background Thyroid hormone is essential for neurological development, particularly in the developing brain. Iodine is the important constituent of thyroid hormone. Its requirement during pregnancy is increased. Elevated neonatal thyroid stimulating hormone (TSH) is a sensitive indicator of iodine insufficiency in pregnant women. Our previous study in the year 2000 demonstrated that median urine...

Journal: :The Journal of biological chemistry 1963
R W TURKINGTON

Previous studies on isolated thyroid cell membranes (1) revealed the presence of an adenosinr triphosphatase (ATPase) activity in these membranes nhicsh showed features characteristic of Na+ and K+ transport by intact cells, and which was enhanced by thyrotropin (TSH’). This ATPase activity was stimulated by Na+ and K+ and required both ions together, was inhibited by ouabain, was Mg++-requirin...

Journal: :JPMA. The Journal of the Pakistan Medical Association 1987
F Agha P Akhter N Jahan R A Khan

One hundred and forty seven clinically proven hyperthyroid subjects were studied using radioimmunoassay techniques for the estimation of serum thyroid hormones and pituitaryTSH concentrations. In females toxic goitre was more frequently seen in the age group 21 to 30 years and in males 31 to 40 years. The mean levels for serum T4, T3, FT4 and FT1 were significantly elevated while the mean level...

2004
Annie W. C. Kung

Thyrotoxicosis has long been known to accelerate bone turnover and thus increase the risk for developing osteoporosis, especially in periand postmenopausal women. Increasingly sophisticated tests of thyroid function have indicated that minor degrees of hyperthyroidism are common in patients taking thyroxine (T4) therapy. Recent reports have suggested that women taking TSH-suppressive doses of T...

2005
P. Y. FORTUNE

An increase in the thyroid activity of teleosts correlated with an increase in environmental temperature has been recorded by Blanc & Buser (1949), Fortune (1953, 1955), and Barrington & Matty (1954); this has not been confirmed by Delsol & Flatin (1956) who found no effect, or by Olivereau (1950,1954, 1955 a, b, c) who demonstrated that increased temperature tended rather to decrease thyroid a...

Journal: :Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2002
H Jack Baskin Rhoda H Cobin Daniel S Duick Hossein Gharib Richard B Guttler Michael M Kaplan Robert L Segal Jeffrey R Garber Carlos R Hamilton Yehuda Handelsman Richard Hellman John S Kukora Philip Levy Pasquale J Palumbo Steven M Petak Herbert I Rettinger Helena W Rodbard F John Service Talla P Shankar Sheldon S Stoffer John B Tourtelot

These clinical practice guidelines summarize the recommendations of the American Association of Clinical Endocrinologists for the diagnostic evaluation of hyperthyroidism and hypothyroidism and for treatment strategies in patients with these disorders. The sensitive thyroid-stimulating hormone (TSH or thyrotropin) assay has become the single best screening test for hyperthyroidism and hypothyro...

Journal: :American journal of human genetics 2008
Lisette Arnaud-Lopez Gianluca Usala Graziano Ceresini Braxton D Mitchell Maria Grazia Pilia Maria Grazia Piras Natascia Sestu Andrea Maschio Fabio Busonero Giuseppe Albai Mariano Dei Sandra Lai Antonella Mulas Laura Crisponi Toshiko Tanaka Stefania Bandinelli Jack M Guralnik Angela Loi Lenuta Balaci Gabriella Sole Alessia Prinzis Stefano Mariotti Alan R Shuldiner Antonio Cao David Schlessinger Manuela Uda Gonçalo R Abecasis Ramaiah Nagaraja Serena Sanna Silvia Naitza

Thyroid-stimulating hormone (TSH) controls thyroid growth and hormone secretion through binding to its G protein-coupled receptor (TSHR) and production of cyclic AMP (cAMP). Serum TSH is a sensitive indicator of thyroid function, and overt abnormalities in thyroid function lead to common endocrine disorders affecting approximately 10% of individuals over a life span. By genotyping 362,129 SNPs ...

Journal: :Acta paediatrica (Oslo, Norway : 1992). Supplement 1999
F Delange

In conditions of iodine deficiency, the frequency distribution of neonatal thyroid-stimulating hormone (TSH) is shifted towards elevated values. Elevated serum TSH in the neonate indicates insufficient supply of thyroid hormones to the developing brain, and therefore constitutes the only indicator that allows prediction of brain damage, which is the main complication of iodine deficiency. This ...

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