نتایج جستجو برای: tenofovir disproxil fumarate
تعداد نتایج: 10210 فیلتر نتایج به سال:
BACKGROUND The preferred regimen for HIV post-exposure prophylaxis (PEP) is based mainly on safety and tolerability because it is given to immunocompetent people without HIV infection for a limited time (28 days). The frequency of adverse events (AEs) may be > 60%. Although AEs are generally not severe, they can lead to lack of adherence and failure to complete the regimen. We evaluated the co-...
BACKGROUND In the absence of an effective vaccine, HIV continues to spread globally, emphasizing the need for novel strategies to limit its transmission. Pre-exposure prophylaxis (PrEP) with antiretroviral drugs could prove to be an effective intervention strategy if highly efficacious and cost-effective PrEP modalities are identified. We evaluated daily and intermittent PrEP regimens of increa...
Introduction: Tenofovir remains the cornerstone drug in various antiretroviral regimens and is commonly associated with renal failure susceptible individuals a biopsy suggestive of proximal tubular injury. Objectives: To investigate clinical, histopathological outcome findings tenofovir-induced nephrotoxicity patients. Patients Methods: Between August 1, 2014, March 31, 2017, an observational s...
Background: Tenofovir alafenamide (TAF) is phosphonamidate prodrug of tenofir that inhibits hepatitis B virus and HIV type-1 reverse transcription. TAF more stable form in plasma than tenofovir disoproxil fumarate (TDF) as choice treatment before. long-term also significantly reduced bone mineral density (BMD) raised serum creatinine, well improved markers renal tubular function. This study aim...
BACKGROUND Resistance to antiretroviral agents remains a leading cause of treatment failure for patients infected with HIV-1. OBJECTIVE To describe the efficacy and safety of tenofovir disoproxil fumarate (tenofovir DF) compared with placebo in patients with detectable viral replication despite current antiretroviral therapy. DESIGN Randomized, double-blind, placebo-controlled study through...
BACKGROUND Antiretroviral pre-exposure prophylaxis reduces sexual transmission of HIV. We assessed whether daily oral use of tenofovir disoproxil fumarate (tenofovir), an antiretroviral, can reduce HIV transmission in injecting drug users. METHODS In this randomised, double-blind, placebo-controlled trial, we enrolled volunteers from 17 drug-treatment clinics in Bangkok, Thailand. Participant...
In a double-blind, phase 3 trial, 663 HIV-infected, virologically suppressed adults were randomized to switch to tenofovir alafenamide (TAF; n = 333) vs. remain on tenofovir disoproxil fumarate (TDF; n = 330), each coformulated with emtricitabine (FTC), while continuing their third agent (boosted protease inhibitor or unboosted third agent). At week 96, 88.6% on FTC/TAF and 89.1% on FTC/TDF had...
Aim: The primary objective of the research work is to develop a effective, sensitive, economical and simple reverse phase HPLC method estimate Emtricitabine tenofovir alafenamide fumarate in its pure binary mixture tablets.
 Study Design: based Quantification Studies.
 Place Duration Study: 1Department Chemistry, Acharya Nagarjuna University,Guntur, Andhra Pradesh between April 2019 A...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید