became symptomatic in October 1998 with right hand weakness and cessation of new words with progression of right sided weakness and decreased sensation over the next month. The computed tomography (CT) and magnetic resonance imaging (MRI) scans demonstrated a large, deep, left frontal periventricular enhancing mass with several cystic areas. A left frontoparietal craniotomy was performed and th...

PATIENT CONCERNS We report a rare case of pancreatic carcinosarcoma involving a 44-year-old woman. The patient complained of discomfort associated with the upper abdomen and jaundice of skin and sclera for 1 week. DIAGNOSES After hospitalization, relevant examinations were completed. The disease was diagnosed as carcinoma of the pancreatic head. INTERVENTIONS Whipple procedure was conducted...

SEE PAGE 1444 P eripheral artery disease (PAD) affects 7 to 8 million persons living in the United States and over 200 million persons worldwide (1,2). In approximately 2% to 3% of patients with PAD, arterial perfusion is inadequate to sustain basal metabolic requirements, resulting in critical limb ischemia (CLI), typically affecting the most distal segments of the leg and manifested as rest p...

ductal adenocarcinoma (PDAC) is often perceived as an incurable disease by both patients and their physicians. While the outcome of most solid tumors has improved over the last 20 years, the median survival for patients with PDAC has steadily remained less than 12 months, even with the best therapeutic regimens currently available [1]. Despite the discouraging statistics, approximately 20% of a...

KEY CLINICAL MESSAGE The survival of multiple myeloma patients has improved very significantly over the last decade. Still median overall survival is inferior to 5 years. A small proportion of patients survive longer than 10 years. In this paper we discuss four cases illustrating the nonhomogeneous clinical presentation and evolution of this subset of patients. Surprisingly, these long survivor...