GERM Cell Tumour is the modern term for a malignant tumour of the testis or ovary. It also includes some tumours that arise in extra-gonadal sites. This volume covers the epidemiology, pathology, diagnosis and clinical management of germ cell tumours. Inevitably the work is a multi-author presentation but the experience of three of the authors from the Department of Oncology at Charing Cross Ho...

conclusions buprenorphine is more suitable for treating opiate addiction in males since it does not affect normal testicular structure and function. results stereological analysis of rat testes showed no significant effect of methadone and buprenorphine administration on the testis volume (p > 0.05). however, microscopic stud­ies of rat tissues in the methadone-administered group showed atrophi...

introduction: male infertility frequently occures after spinal cord injury (sci). however little in known about the acute effect of sci on male reproductive function. this study examined the spermatogenic changes during acute phase of sci. material and metods: in experimental groups sci was produced in male rats by t9 laminectomy and spinal cord transsection (n=23, age=70 days). control groups ...

Tamoxifen is a synthetic, nonsteroidal Type I antiestrogenic compound that competitively blocks estrogen receptors with a mixed antagonist-agonist effect. The manifestation of these different actions depends on each species, organ, tissue and cell type considered. Very little is known about the effect of antiestrogens in dogs. The objectives of this study were to determine the effects of tamoxi...

Samenvatting In dit case report beschrijven wij een 36-jarige man, die zich op de Spoedeisende Hulp presenteerde met pijn in rechterflank en rechter testis, bleek te berusten segmenteel infarct van testis. Een testisinfarct is zeldzame oorzaak acute scrotale echografisch lastig onderscheiden testistumor. De vaak idiopathisch. Predisponerende factoren zijn onder andere infectie, trauma hematolog...

BACKGROUND Various kinds of transmembrane and secreted proteins play pivotal roles in development through cell-cell communication. We previously reported that Obif (Osteoblast induction factor, Tmem119), encoding a single transmembrane protein, is expressed in differentiating osteoblasts, and that Obif-/- mice exhibit significantly reduced bone volume in the femur. In the current study, we char...

BACKGROUND The aim of this study was to investigate whether there is a need for diagnostic biopsies in men with obstructive azoospermia (OA). METHODS Sixty-three adult men with OA due to vasectomy, bilateral inflammation or bilateral aplasia of the vas deferens were included in the study. We determined testicular volume, sexual hormone levels and testicular histologies of right and left teste...

The objectives of the present work were 3-fold. First, a new method for estimating daily sperm production was validated. This method, in turn, was used to evaluate testis output as well as deferent duct throughput. Next, this analytical approach was evaluated in 2 experiments. The first experiment compared left and right reproductive tracts within roosters. The second experiment compared reprod...

To cite: Chaudhary R, Singh K, Jain A, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2014205893 DESCRIPTION A 40-year-old man with quadriparesis presented in January 2014 with pain and swelling in the left testis for 2 weeks. He had sustained cervical spine injury 2 years earlier and had an indwelling urethral catheter since then. He had undergone a right...