vitamin c, an antioxidant substance soluble in water, can react with amino groups of proteins to form schiff bases. as diabetes leads to glycation of various protein which has effect on structure and biochemical activity of them, the inhibition of this process seems very vital. for several years researches in this field have done their best to recognize the antidiabetics compounds. the aim of t...

patients and methods this prospective cohort study was performed on 90 diabetic type 2 patients with microalbuminuria, who were selected according to the consecutive sample selection method during 6 years. data were collected through regular and systematic measurements of serum albumin as the response variable and body mass index, systolic and diastolic blood pressure, the duration of diabetes,...

introduction: kidney disease is a major public health challenge worldwide. epidemiologic data suggest a significant relationship between underlying diseases and decrease in glomerular filtration rate (gfr). clinical studies and laboratory research have shown that the mentioned parameter is effective in development and progression of the renal disease per se. in this study, we used learning-base...

curcumin is a natural polyphenolic compound with anti-cancer, anti-inflammatory, and anti-oxidation properties. low water solubility and rapid hydrolytic degradation are two challenges limiting use of curcumin as therapeutic agent. in the current study, the role of the bovine serum albumin (bsa), β-lactoglobulin and casein, as food-grade biopolymers and safe drug delivery systems, on the physic...

background: protein energy malnutrition and inflammation in hemodialysis (hd) patients often leads to the malnutrition inflammation complex syndrome or atherosclerosis malnutrition and inflammation related to the atherosclerotic cardiovascular disease.   this syndrome occurs in patients undergoing dialysis for a long time and is accounted as an important factor of mortality among these patients...