The aim of this study compares to the increase in tissue temperature and the thermal histological effects of ultrasonic scalpel, bipolar and unipolar electrosurgery incisions in the tongue tissue of rabbits. This study evaluates the histopathological changes related to thermal change and the maximum temperature values in the peripheral tissue brought about by the incisions carried out by the th...

To clarify the role of peroxisome proliferator activated receptor gamma (PPARgamma) in neuropathic pain, we examined the effect of pioglitazone, a PPARgamma agonist, on tactile allodynia and thermal hyperalgesia in a neuropathic pain model. Mice were subjected to partial sciatic nerve ligation (PSL) and given pioglitazone (1 - 25 mg/kg, p.o.) once daily. PPARgamma was distributed in the neurons...

The thermal conductivity of superconducting MgB 2 was studied in both the superconducting and normal state region. The latter is almost equally determined by the electronic-and the lattice thermal conductivity. In the superconducting state, however, the lattice thermal conductivity is larger. The electronic thermal conductivity below T c was derived from the experimental data considering the Ba...

Combining radiofrequency (RF) ablation with i.v. liposomal doxorubicin (Doxil) increases intratumoral doxorubicin accumulation and tumor destruction. The purpose of this study was to characterize and better define the specific parameters of such treatment in an animal tumor model. Four hundred R3230 mammary adenocarcinoma nodules were implanted in 250 Fischer rats. First, paired tumors received...

Drug-induced toxic epidermal necrolysis (TEN) and acute cutaneous graft-versus-host reaction (GVHR) under immunopreventive therapy share some histopathological resemblance. So far, there are no serum biomarkers and no immunohistochemical criteria distinguishing with confidence and specificity the skin lesions of TEN and GVHR. Both diseases present as an inflammatory cell-poor necrotic reaction ...

Thermal conductivity of superconducting MgB 2 was studied in both the superconducting and the normal state region. The latter is almost equally determined by the electronic-and the lattice contribution to the total thermal conductivity. In the superconducting state, however, the lattice contribution is larger. The electronic thermal conductivity below T c was derived from the experimental data ...

BACKGROUND The mechanisms underlying cyclin-dependent kinase 5 (Cdk5)-mediated thermal hyperalgesia induced by inflammation remain poorly understood. In the present study, we examined thermal hyperalgesia provoked by peripheral injection of complete Freund׳s adjuvant (CFA) to test for Cdk5 signaling in the spinal dorsal horns of rats through the p38 mitogen-activated protein kinase (p38 MAPK) s...

endodontic intervention in necrotic immature permanent teeth is usually a clinical challenge. with appropriate case selection, regenerative treatment can be effective, providing a desirable outcome. however, there is still no consensus on the optimal disinfection protocol or the method to achieve predictable clinical outcome. this article presents two cases of regenerative treatment in necrotic...