The global variability of ultra-thin body and buried oxide (UTBB) MOSFETs in subthreshold and off regimes of operation is analyzed. The variability of the off-state drain current, subthreshold slope, drain-induced barrier lowering (DIBL), gate leakage current, threshold voltage and their correlations are considered. Two threshold voltage extraction techniques were used. It is shown that the tra...

Over 200 measurements of the minimum damped sinusoidal current and energy for transchest electrical ventricular defibrillation (ventricular defibrillation threshold) were made to determine the stability and precision of threshold data in 15 pentobarbital-anesthetized dogs. Threshold was determined by repeated trials of fibrillation and defibrillation with successive shocks of diminishing curren...

Dynamic spike threshold plays a critical role in neuronal input-output relations. In many neurons, the threshold potential depends on the rate of membrane potential depolarization (dV/dt) preceding a spike. There are two basic classes of neural excitability, i.e., Type I and Type II, according to input-output properties. Although the dynamical and biophysical basis of their spike initiation has...

The radiative corrections of order α for the charged and neutral current neutrino-deuterium disintegration for energies relevant to the SNO experiment are evaluated. Particular attention is paid to the issue of the bremsstrahlung detection threshold. It is shown that the radiative corrections to the total cross section for the charged current reaction are independent of that threshold , as they...

The radiative corrections of order α for the charged and neutral current neutrino-deuterium disintegration for energies relevant to the SNO experiment are evaluated. Particular attention is paid to the issue of the bremsstrahlung detection threshold. It is shown that the radiative corrections to the total cross section for the charged current reaction are independent of that threshold , as they...

The radiative corrections of order a for the chargedand neutral-current neutrino-deuterium disintegration for energies relevant to the SNO experiment are evaluated. Particular attention is paid to the issue of the bremsstrahlung detection threshold. It is shown that the radiative corrections to the total cross section for the charged current reaction are independent of that threshold, as they m...

This study was conducted to determine the effects of clofilium phosphate and bretylium tosylate on ventricular defibrillation threshold. Dogs were anesthetized with pentobarbital and subjected to repeated fibrillation-defibrillation episodes. Defibrillation thresholds were determined at 15-min intervals, using underdamped 5--6 msec sinusoidal current shocks, from 30 min before drug injection to...

The nucleus accumbens (NA) has an integrative role in behavior and may mediate addictive and psychotherapeutic drug action. Whole cell recording techniques were used to characterize electrophysiologically and pharmacologically high- and low-threshold voltage-dependent Ca2+ currents in isolated NA neurons. High-threshold Ca2+ currents, which were found in all neurons studied and include both sus...

Electronic retinal prostheses represent a potentially effective approach for restoring some degree of sight in blind patients with retinal degeneration. However, levels of safe electrical stimulation and the underlying mechanisms of cellular damage are largely unknown. We measured the threshold of cellular damage as a function of pulse duration, electrode size, and number of pulses to determine...

1. The whole-cell variation of the patch clamp technique was used to study the effect of calcitonin gene-related peptide (CGRP) on voltage-gated calcium currents in acutely dissociated rat nodose ganglion neurones and to determine if its effects were mediated via a guanine nucleotide binding (G) protein. 2. Both low- and high-threshold calcium current components were present in nodose ganglion ...