BACKGROUND We investigated changes in the International Normalized Ratio (INR) and its measurement interval in patients with thromboembolic events who were treated by low intensity anticoagulation therapy after isolated mechanical aortic valve replacement. MATERIALS AND METHODS Seventy-seven patients who underwent surgery from June 1990 to September 2006 were enrolled in the study and observe...

Background: So-called heterotaxy, better called bodily isomerism, is associated with increased frequency of thrombocytosis and thromboembolic events in childhood. This is likely mediated by splenic dysfunction present with isomerism. Data for adults with isomerism is lacking with a paucity of data regarding thrombosis and isomerism. This study aimed to determine the risk of thrombocytosis and t...

BACKGROUND AND AIM Interruption of anticoagulant treatment with warfarin or non-vitamin K antagonist oral anticoagulants (NOAC) represents a vulnerable period with an increased risk of thromboembolic events. What is the incidence of thromboembolic events in real-life patients with non-valvular atrial fibrillation treated with NOAC who had a discontinuation or cessation of treatment in compariso...

OBJECTIVE To determine whether the finding of antiphospholipid antibodies in patients with venous thromboembolic episodes should influence the duration of treatment with anticoagulant drugs by mouth. METHODS A retrospective study was carried out in 19 patients with antiphospholipid antibodies and a history of venous thromboembolic episodes. The median follow up from the first venous thromboem...

the clinical management of pulmonary embolism and deep venous thrombosis of the legs are similar and requires prolonged anticoagulation therapy. the standard diagnostic approach in patients suspected of pulmonary embolism is ventilation-perfusion (v/q) lung scan and compression ultrasonography to detect deep venous thrombosis. this retrospective study analyzed the role of v/q lung scan and comp...

While treating patients with endometrial hyperplasia, the physician may face both bleeding and thrombotic complications, particularly, during hormonal or surgical treatment, which significantly increases risk of these complications. In addition, complications in gynecological result from congenital acquired thrombophilia, blood flow disorders (blood stasis), vascular wall damage, that is, class...

conclusions we observed acceptable results regarding both efficacy and safety with 62.5 mg of bosentan, twice daily in this group of patients. further clinical trials investigating pah with lower dosages of bosentan may be warranted. results no adverse drug reaction was observed during the follow-up. clinical worsening occurred in six (14%) patients, at least one year after treatment, two of th...

Background: Thromboembolic disorders are one of the important causes leading to death. In Siddha system medicine, many drugs have been mentioned in literature and their thrombolytic potential needs be scientifically evaluated. Aim: The study aims perform Silico computational studies Phytoconstituents formulation Sikkanjar Manapagu (SM) evaluate its potential. Methods: Autodock program was used ...

The clinical management of pulmonary embolism and deep venous thrombosis of the legs are similar and requires prolonged anticoagulation therapy. The standard diagnostic approach in patients suspected of pulmonary embolism is ventilation-perfusion (V/Q) lung scan and compression ultrasonography to detect deep venous thrombosis. This retrospective study analyzed the role of V/Q lung scan an...