In order to further optimize the treatment strategy for the patients with acute basilar artery occlusion, we were dedicated to study the therapeutic effects and influential factors in the process of treated basilar artery occlusion with thrombolytic combined vascular interventional therapy. 75 patients with acute basilar artery occlusion treated with arterial thrombolytic therapy were analyzed ...

OBJECTIVE Thrombolytic therapy for acute ischemic stroke was implemented into clinical routine 4 yrs ago. Unfortunately, at present <2% of eligible patients receive thrombolytic therapy. We present an overview of all hitherto completed trials of intravenous thrombolytic therapy for carotid artery stroke including recommendations for therapy and diagnostic procedures and their impact on patient ...

Background. Migraine is prevalent in young patients and a frequent stroke mimic. To distinguish stroke mimics from true stroke can be difficult, and there is a possibility of misdiagnosing a stroke as a migrainous attack in patients with migraine. We aimed to investigate if a history of migraine affects the rate of thrombolytic therapy in young stroke patients. Methods. All patients below 50 ye...

BACKGROUND AND PURPOSE In a feasibility and safety study of thrombolytic therapy in acute ischemic stroke, we explored the usefulness of measurements of regional cerebral blood flow. METHODS Twenty-three patients with acute ischemic stroke were treated with 100 mg recombinant tissue plasminogen activator infused intravenously over 1 hour. Thrombolytic therapy was initiated 78 to 355 minutes a...

The overall aim of reperfusion therapy for patients presenting with an ST-segment elevation myocardial infarction (STEMI) is to restore normal blood flow in the infarct-related artery as rapidly and completely as possible, and thus myocardial perfusion. This can be achieved by the administration of thrombolytic therapy (either pre-hospital or in hospital) or by primary percutaneous coronary int...

objective: to evaluate the efficacy and safety of intravenous and catheter directed thrombolysis by recombinant tissue plasminogen activator (alteplase) in the patients with non-traumatic acute limb ischemia (ali). methods: this was a randomized clinical trial being performed between 2009 and 2011 in mashhad university of medical sciences. we included those patients who were<75 years, with symp...

BACKGROUND AND PURPOSE The identification of genetic and environmental factors that could improve the benefit/risk ratio of thrombolytic therapy in patients with ischemic stroke is crucial. METHODS We studied the role in the efficacy and side-adverse effects of thrombolytic therapy in stroke of 2 factors involved in the structure and stability of fibrin clot: fibrinogen levels and factor XIII...

Thrombolysis and primary angioplasty are both recommended reperfusion strategies for elderly patients presenting with myocardial infarction (MI). Primary angioplasty is most beneficial in high-risk patients. While the elderly have a high absolute risk of dying or developing complications after MI, they also have an increased risk of intracranial haemorrhage if they are given thrombolytic therap...

Thrombolytic therapy is a practical, effective approach to the management of acute myocardial infarction that is widely used in Europe today. Early European trials demonstrated a clear reduction in mortality in patients who received thrombolytic therapy compared with those given conventional treatment. The findings of experimental studies suggest that early reperfusion of the infarct-related ar...

A previous study suggested that WUS onset time is close to wake-up time [2] . For this reason, WUS might respond to thrombolytic therapy. The clinical benefits of acute thrombolytic therapy for IS patients requires the presence of a salvageable penumbra. Considering the estimated previously reported penumbra rates, Koton et al. estimated that 164–328 of 820 WUS patients could be additional pote...