نتایج جستجو برای: thrombotic factors
تعداد نتایج: 1089911 فیلتر نتایج به سال:
Tissue factor (TF) plays a role in thrombogenesis. TF initiates blood coagulation resulting in the generation of protease coagulant mediators (FVIIa, FXa, and FIIa) and fibrin production. TF hypercoagulablility directly contributes to thrombus formation resulting from the major events of fibrin deposition and FIIa-induced platelet activation/aggregation. In addition, blood coagulation indirectl...
several studies have assessed association between helicobacter pylori infection and thrombotic ischemic stroke. this study was designed to investigate the association between this organism and ischemic strokes. antibody against h. pylori (hp igg) was measured in 81 patients with stroke and 43 subjects without stroke. hp igg titer more than 20u/ml was defined as positive. 67.4% of control subjec...
Thrombotic microangiopathies (TMAs) are a group of life-threatening disorders characterized by thrombocytopenia, fragmentation of erythrocytes, and ischemic organ damage. Genetic disorders, autoimmune disease, and cancer are risk factors for TMAs, but an additional, unknown trigger is needed to bring about acute disease. Recent studies suggest that DNA and histones are released during inflammat...
The presence of anti-phospholipid (aPL) is necessary but not sufficient to induce a thrombotic event. The "second hit" hypothesis suggested that an additional trigger may be needed to develop a vascular event in aPL carriers. In this article, pro and con of primary thromboprophylaxis in aPL carriers is deeply discussed, concluding that univocal data are not available, due to conflicting results...
OBJECTIVE Weight gain and growth in early life may influence adult pro-inflammatory and pro-thrombotic cardiovascular risk factors. METHODS Follow-up of a birth cohort in New Delhi, India, whose weight and height were measured every 6 months until age 21 years. Body mass index (BMI) at birth, during infancy (2 years), childhood (11 years) and adulthood (26-32 years) and BMI gain between these...
Background & Aims: Genetic mutation, 1691G> A common polymorphism in a gene that is inherited coagulation Factor 5 is associated with increased risk of thrombosis. This mutation in different populations can develop in the prognosis of thrombotic disorders, cardiovascular disorders recurrent miscarriage and other thrombotic factors are useful. Study using appropriate strategies such as review o...
The scientific debate on oral contraceptives (OCs) therapy and thrombotic diseases continues unabated. This retrospective casecontrol study was intended to evaluate the age specific effects of oral contraceptives and smoking on the risk of deep venous thrombosis, pulmonary thromboembolism and arterial thombosis in women under 50 years. The study included evaluation of registry records of Bulgar...
Thrombosis can cause localized ischemia and tissue hypoxia, and both of these are linked to cancer metastasis. Vascular micro-occlusion can occur as a result of arrest of circulating tumour cells in small capillaries, giving rise to microthrombotic events that affect flow, creating localized hypoxic regions. To better understand the association between metastasis and thrombotic events, we gener...
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