Observational studies have demonstrated that maternal thyroid dysfunction and thyroid autoimmunity in pregnancy may be associated with adverse obstetric and fetal outcomes. Treatment of overt maternal hyperthyroidism and overt hypothyroidism clearly improves outcomes. To date there is limited evidence that levothyroxine treatment of pregnant women with subclinical hypothyroidism, isolated hypot...

PURPOSE To evaluate the prevalence of autoimmune thyroid disease and thyroid dysfunction in patients with primary Sjögren's syndrome. PATIENTS AND METHODS Thyroid function of 33 patients with primary Sjögren's syndrome was clinically and biochemically evaluated. Thyroid hormones and autoantibodies against thyroid peroxidase, thyroglobulin, and thyroid hormones were measured. RESULTS Autoimm...

conclusions thyroid dysfunction was not higher in sle patients compared to healthy individuals. however, anti-tg antibodies were higher in sle patients. it has not yet been established that thyroid function tests should be performed routinely in sle patients. results the mean age of sle patients and controls were 32.16 ± 9.19 and 32.48 ± 9.47 years, respectively (p = 0.821). patients had signif...

BACKGROUND Several of the currently used anticancer drugs may variably affect thyroid function, with impairment ranging from modified total but not free concentration of thyroid hormones to overt thyroid disease. SUMMARY Cytotoxic agents seem to alter thyroid function in a relatively small proportion of adult patients. Anticancer hormone drugs may mainly alter serum levels of thyroid hormone-...

Aim: To assess the risk factors for renal dysfunction in a heterogeneous population. determine age and sex wise distribution of eGFR Urinary spot Protein- Creatinine ratio (UPCR) estimate lipid profile thyroid their role as factor dysfunction. Introduction: Chronic Kidney Disease (CKD), is major health problem India. As per Diseases Improving Global Outcomes (KDIGO) 2012, CKD defined1 abnormali...

BACKGROUND Subclinical thyroid dysfunction is common among older people and has been associated with decreased functional capacity but with conflicting data. The aim of this study was to assess the association between subclinical thyroid dysfunction and functional capacity in an elderly population. METHODS We included 5182 participants with a mean age of 75.2 years from the Prospective Study ...

CONTEXT Heart failure (HF) is a major cause of morbidity and mortality in Europe and in the United States. The aim of this review article was to assess the results of the prospective studies that evaluated the risk of HF in patients with overt and subclinical thyroid disease and discuss the mechanism of this dysfunction. EVIDENCE ACQUISITION Reports published with the following search terms w...

PURPOSE The purpose of this study was to evaluate short-term thyroid dysfunction and related risk factors in pediatric patients who underwent hematopoietic stem cell transplantation (HSCT) during childhood. METHODS We studied 166 patients (100 boys and 66 girls) who underwent HSCT at the Catholic HSCT Center from January 2004 through December 2009. The mean age at HSCT was 10.0±4.8 years. Thy...

Our knowledge about thyroid function during pregnancy has made rapid strides in the recent past. However, there are not much published reports in anesthesia literature regarding these newer developments. Even though an anesthesiologist is not the primary care physician, he/she may occasionally encounter pregnant patients with thyroid dysfunction in routine practice of anesthesia. This article a...

Background: Hyperthyroid has various effects on the cardiovascular system. Cardiac arrhythmias ranging from sinus tachycardia to atrial fibrillation and low/high cardiac output state congestive heart failure are observed in patients with hyperthyroidism. If hyperthyroidism is recognized treated early, dysfunction could be corrected. This case presentation will discuss importance of thyroid func...