2014 Aim: The aim of this study was to determine the relationship between thyroid disorders and prolactin in patients with and without lupus activity. Patients & methods: Women with systemic lupus erythematosus (SLE) were evaluated for lupus activity. Serum tri-iodothyronine (T3), serum thyroxine (T4) and thyroid-stimulating hormone (TSH), anti-thyroid peroxidase (anti-TPO) anti-thyroglobulin (...

BACKGROUND To date, the relationship between thyroid dysfunction and subcortical ischemic vascular disease (SIVD)-induced cognitive impairments still remains elusive. METHODS Cognitive performances were examined in 215 participants, including 54 healthy participants, 52 SIVD patients with no dementia (SIVDND), 55 patients with mild cognitive impairment (SVMCI), and 54 patients with vascular d...

Exosomes are 30-100 nm, membrane-bound vesicles containing specific cellular proteins, mRNAs, and microRNAs that take part in intercellular communication between cells. A possible role for exosomes in thyroid function has not been fully explored. In the present study, FRTL-5 rat thyroid cells were grown to confluence and received medium containing either thyroid stimulating hormone (TSH), exoge...

Pregnancy has variable effects on thyroid hormone concentrations throughout pregnancy as well as being associated with goiter. The latter is largely preventable by ensuring optimal iodine intake of at least 200 microg/d. Immunologic changes in pregnancy include a so-called T(H)2 shift that reverts to T(H)1 status around birth or early in the postpartum period. Hyperthyroidism during gestation, ...

A 14-year-old boy was admitted to our hospital after being diagnosed at a local clinic with bilateral carotid artery stenoses (Moyamoya disease) and mild thyrotoxicosis. A blood examination showed suppressed TSH and elevated triiodothyronine and thyroxine levels; however, he was negative for anti-thyrotropin receptor antibody (TRAB) and thyroid stimulating antibody (TSAB). Concern about a possi...

Background: Hypothyroidism was the diagnosed and treated as a result of health related quality life issues. The aim this study that to evaluate effect IL-36 γ, Tg-Ab TOP-Ab in Hashimoto’s Thyroiditis (HT). Study design: This cross sectional conducted at Rawal Institute sciences, Islamabad duration six month, from April 2022 September 2022. Methods: A total number patients n=150 which divided in...

receptors was investigated. IgG from Graves’ sera with high thyroid-stimulating antibody activity were diluted in IgG from a pool of normal human serum (so that each sample contained the same amount of total IgG) and incubated overnight at 0°C with labelled thyrotropin and membranes solubilized with 0.5 % Triton. The mixtures were then analysed by chromatography on Sepharose or by poly(ethy1ene...

Rabbits were immunized with bovine thyroid-stimulating hormone (bTSH), bovine Inteinizing hormone (bLH), and their subunits. In two immunization experiments, thyroid-stimulating activity was found in the serum of 6 out of 12 rabbits immunized with bTSHbeta subunits. The thyroid-stimulating activity in the anti-bTSHbeta sera was greater at 2 h than at 8, was eluted with the globulin fraction fro...