Objective: It was aimed to investigate the effects of boric acid on some lncRNAs and invasion in PANC-1 MIA PaCa-2 pancreatic cancer cells. Materials Methods: The cell viability were investigated using XTT test chambers, respectively. lncRNA H19 UCA1 expressions evaluated TCGA data. Its these genes determined by qRT-PCR analysis. Results: IC50 doses calculated as 14.25 mM cells 15.71 PaCa-2. da...

Abstract Background About 90% of cancer-related deaths are due to metastasis cancer cells, and angiogenesis is a critical step in this process. sFLT01 novel fusion protein dual-targeting agent that neutralizes both VEGF PlGF proangiogenic activities. GRP78 dual effect tumor growth could be activated under stimulation. The current study was designed investigate the inhibitory impact on VEGF/GRP7...