Soon after identification of the platelet membrane glycoprotein (GP) IIb/IIIa, it has become a target of antiplatelet therapy. There are 3 intravenous GP IIb/IIIa receptor inhibitors, namely- eptifibatide, tirofiban and abciximab, used in the contemporary clinical practice, particularly in patients with acute coronary syndrome undergoing percutaneous coronary intervention (PCI). The aim of the ...

Background—The present study describes the effects of tirofiban, a nonpeptide platelet glycoprotein (GP) IIb/IIIa receptor blocker, on the characteristics of culprit lesions in patients with unstable angina (UA) or non–Q-wave myocardial infarction (NQWMI). Methods and Results—Of 1915 patients enrolled in PRISM-PLUS, 1491 had a readable film obtained a median of 65 hours after randomization. A c...

c s c u r r d t m t p s p a t l t a B b w d a t a 0 d S o s rug-eluting stents have been the most successful strategy or the prevention of restenosis after percutaneous coronary nterventions (1). In line with this, the STRATEGY Single High-Dose Bolus Tirofiban and Sirolimus Eluting tent versus Abciximab and Bare Metal Stent in Acute yocardial Infarction) study showed a marked decrease in he nee...

A 74-year-old male patient was admitted to our emergency department with post-MI angina. On account of the anginal complaint that continued for three days, a coronary artery angiography was undertaken. A percutaneous transluminal coronary angioplasty was performed, followed by the implantation of a coronary stent, and coronary perfusion (TIMI-3) was achieved in the left anterior descending arte...

Previous studies have shown that intracoronary (IC) nitroprusside (NTP) injection is a safe and effective strategy for the treatment of no-reflow (NR) during percutaneous coronary intervention (PCI). The present study tested the hypothesis that, on the basis of thrombus aspiration for the treatment of ST-segment elevation myocardial infarction (STEMI), the selective IC administration of a fixed...

The presence of a thrombus in the left main coronary artery is a rare but serious situation. Although there are no clear guidelines for such cases, a coronary artery bypass grafting (CABG) surgery is generally performed. Also, in the literature, there are limited reports on cases treated successfully through percutaneous procedures or medical therapy. In this article, we report the case of a pa...

Acute ST-segment elevation myocardial infarction (STEMI) complicated with multiple coronary artery thrombosis is a rare clinical situation and is associated with poor prognosis. A 63-year-old male patient was admitted to the emergency department with sudden chest pain that had started three hours ago. The patient was diagnosed with acute inferior STEMI. The emergency coronary angiography showed...