Recent work has indicated that evidence supporting a role for tocopherol in electron transport should be re-evaluated. The direct demonstration of the inhibitory nature of solvents on enzymes of the respiratory chain (1) and nonspecific restoration of this activity by various lipids (2, 3) are the major objections to studies which employed isooctane extraction. However, other evidence based on ...

Several lines of evidence suggest that oxidatively modified low density lipoprotein (LDL) is atherogenic and that antioxidants may protect LDL against oxidation. In addition, cigarette smoking is known to induce oxidant stress. We have examined the effect of ingestion of the antioxidants D,L-alpha-tocopherol (vitamin E) and beta-carotene and of smoking on the resistance of LDL against copper-me...

Several lines of evidence suggest that oxidatively modified low density lipoprotein (LDL) is atherogenic and that antioxidants may protect LDL against oxidation. In addition, cigarette smoking is known to induce oxidant stress. We have examined the effect of ingestion of the antioxidants D,L-ar-tocopherol (vitamin E) and 0-carotene and of smoking on the resistance of LDL against copper-mediated...

This study determined the dietary effects of pomegranate peel powder meal (PPPM) supplementation on growth performance, digestibility, carcase and organ weights, serum, some meat antioxidant enzyme indices Cobb 500 birds. Birds (n = 432) were randomly assigned to six experimental groups four replicates each fed either diets supplemented with 2, 4, 6 8 g/kg PPPM (PPPM2, PPPM4, PPPM6 PPPM8), 0% a...

Hypercholesterolemic diets are associated with oxidative stress that may contribute to hypercholesterolemia by adversely affecting enzymatically-generated oxysterols involved in cholesterol homeostasis. An experiment was conducted to examine whether the cholesterol-lowering effects of the antioxidants selenium and α-tocopherol were related to hepatic oxysterol concentrations. Four groups of mal...

BACKGROUND The aim of this study was to assess the effect of diet supplementation with L-ascorbic acid (500 mg/L), tocopherol (3 mg/kg b.w.), and/or a water soluble analog of tocopherol (Trolox) (48 mg/L) on ion transport in the colon of rats subjected to a chronic exposure (9 months) to 0.1% lead acetate in drinking water. MATERIAL/METHODS The electrophysiological parameters of the colon wal...