Background: Pharmacokinetic properties, dosing regimen, and potency at the site of action are among the factors that influence activity of a corticosteroid. The potency of a corticosteroid at the site of action is determined significantly by its affinity to the glucocorticoid receptor. Recent literature on topical corticosteroids reveals an increasing emphasis on comparative relative receptor a...

a series of sorbents containing various amounts of borate groups were prepared by chemical immobilization ofp-aminoethylphenylboric acid on a copolymer- treated organosilane spacer glass plates. it was found thatbaker's yeast cells selectively adhered to these supports. yeast cells stained with procion red he-3b formeddenser and more stable layer on the copolymer-grafted supports compared onto ...

Commercial grapefruit seed extracts (GSE) were extracted with chloroform. The solvent was evaporated, and the resulting solid was subsequently analyzed by high-performance liquid chromatography, electrospray ionization mass spectrometry, nuclear magnetic resonance (NMR) spectroscopy, and elemental analysis (by proton-induced X-ray emission [PIXE] analysis). The main constituent was identified a...

We have constructed a high-pT trigger for the HERA-B experiment at DESY. The HERA-B experiment produces B mesons by inserting wire targets into the halo of the proton beam circulating in HERA. The high-p T trigger records events that contain tracks that have high transverse momentum with respect to the beam. Such a trigger is efficient for recording B → ππ, B → Kπ, Bs → K K, Bs → D − s π , and ...

Introduction: Recently, an approach exploiting the proton therapy biological enhancement by using Boron atoms injected inside a tumor, has been proposed. Three alpha particles with an average energy around 4MeV are emitted from the point of reaction between a proton and boron. In addition, the 719 keV prompt gamma emitted by the proton Boron fusion reactions can be used for on-...

The F-ATPase of chloroplasts couples proton flow to ATP synthesis, but is leaky to protons in the absence of nucleotides. This "proton slip" can be blocked by small concentrations of ADP or by inhibitors of the channel portion, CF0. We studied charge flow through the ATPase by flash spectrophotometry and analyzed the inhibition of proton slip by nucleotides, phosphate/arsenate, and insufficient...

Eosinophilic esophagitis (EoE) is a chronic esophageal disease increasingly recognized in adults for its gastrointestinal manifestations. This paper discusses a young woman with EoE who presented with persistent hiccups and intermittent dyspepsia. The patient was initially treated with trials of both H(2) blocker and proton pump inhibitor. However, her hiccups resolved only after treatment with...

The ability of topical timolol and epinephrine to decrease the 0-adrenergic responsiveness of the cornea and iris-ciliary body of albino and pigmented rabbits is reported. The time course of the decrease in responsiveness was determined by comparing in vitro, /?-adrenergic stimulated cyclic AMP synthesis in these tissues from in vivo drug treated and contralateral, untreated eyes. In the cornea...

Abstract The reaction of seventeen borane derivatives five-membered N-heterocyclic rings (BNHRs) with CO 2 has been studied by means DFT calculations. Several non-covalent complexes between the BNHRs and which evolve through a TS in single adduct for each BNHR have identified. calculated IRC allowed to identify complex involved case. stationary points reactions analyzed distortion/interaction p...

The reaction of gas-phase oxidation of 4-methylpyridine on individual V2O5, binary and ternary vanadium-oxide catalysts was studied. These catalysts were modified by additives of SnO2 and TiO2. It was found that modifying V2O5 leads to increase the activity of binary contacts. Upon transition from binary V2O5<...