Juvenile idiopathic arthritis (JIA) is the most frequent rheumatic disease of childhood and uveitis its common extra-articular manifestation. JIA-associated (JIA-U) one main causes visual impairment in children represents a major challenge for pediatrician ophthalmologist, due to insidious onset sight-threatening complications. Topical glucocorticoids are first line treatment, followed by conve...

Orally inhaled therapies are a cornerstone of lung health maintenance in CF. Topical application of drugs in the airways increases the efficacy and reduces the systemic exposure and toxicity of these agents. Most CF patients are treated with aerosolized therapies, and many take multiple inhaled drugs on a daily basis. Treatments for bronchodilation, inflammation, airway clearance and early or c...

The skin microbiome is an essential barrier for preventing the invasion of pathogens and regulating immune responses. When this disrupted, several dermatoses, including acne vulgaris, may arise. Most people will experience starting at onset puberty continuing into adolescence; a significant percentage those individuals continue to suffer from it adulthood. Although common, dermatosis usually ha...

The majority of atopic dermatitis (AD) patients respond satisfactorily to gentle bathing, frequent moisturizing, and topical medications. Second-line therapies for AD should be used in recalcitrant cases or in patients with uncontrolled disease despite compliance with first-line measures and avoidance of allergens. Recommended advanced therapies include phototherapy, especially narrowband ultra...

PURPOSE OF REVIEW To review recent literature on the topical treatment of allergic skin diseases to help clinicians make informed evidence-based decisions. RECENT FINDINGS Twenty-four publications were identified from a PubMed search of randomized controlled trials and systematic reviews of topical treatment of atopic dermatitis and allergic contact dermatitis published from 1 January 2013 to...

Background: Narrow band Ultraviolet B (NBUVB) has been used successfully for the treatment of vitiligo. Recently, topical calcipotriol has also been used as immunotherapy or as a part of combination therapies. The aim of this study was to compare the clinical efficacy and safety of NBUVB and NBUVB plus topical calcipotriol in the treatment of generalized vitiligo.Methods: NBUVB phototherapy was...