Whittaker, V. P. (1971a) Ann. N. Y. Acad. Sci. 183, 21 Whittaker, V. P. (1971b) Advan. Cytopharmacol. 1, 319 Whittaker, V. P. (1972) in Structure and Function of Synapses (Pappas, G. D. & Purpura, D. P., eds.), Raven Press, New York Whittaker, V. P. & Barker, L. A. (1971) Methods Neurochem. 2, 1 Whittaker, V. P. & Sheridan, M. N. (1965) J. Neurochem. 12, 363 Whittaker, V. P., Michaelson, I. A. ...

The natural electrical phenomena fascinated humans since antiquity. The electrical discharges produced by the torpedo fish were highly appreciated among ancient physicians as Hippocrates, Scribonius Largus and Galen and were prescribed for headache, gout and prolapsed anus. In the medieval period, torpedo's electrical properties were attributed to occult powers, while Renaissance physicians' an...

Two monoclonal antibodies (mabs) previously prepared against Torpedo acetylcholine receptor are shown to recognize a synthetic nonadecapeptide corresponding to lys360-glu377 of the gamma subunit. The reaction was demonstrated by solid-phase enzyme-linked immunoabsorbent assays, by inhibition of binding of the mabs to receptor, and by immunoprecipitation of the peptide conjugated to bovine serum...

Using an affinity-purified monospecific polyclonal antibody against bovine brain synapsin I, the distribution of antigenically related proteins was investigated in the electric organs of the three strongly electric fish Torpedo marmorata, Electrophorus electricus, Malapterurus electricus and in the rat diaphragm. On application of indirect fluorescein isothiocyanate-immunofluorescence and using...

We have performed an electrophysiological analysis of the recently cloned Torpedo marmorata Cl- channel. Functional expression of Cl- channels in oocytes of Xenopus laevis previously injected with cRNA yielded an outward-rectifying current activated by hyperpolarization. Replacement of Cl- with other anions significantly reduced or inhibited the current. Single-channel recordings from cell-atta...

In Drosophila, the dorsal-ventral polarity of the egg chamber depends on the localization of the oocyte nucleus and the gurken RNA to the dorsal-anterior corner of the oocyte. Gurken protein presumably acts as a ligand for the Drosophila EGF receptor (torpedo/DER) expressed in the somatic follicle cells surrounding the oocyte. cornichon is a gene required in the germline for dorsal-ventral sign...