Total-body irradiation (TBI), when given as part of bone marrow transplantation (BMT), works by enhancing immune suppression and by exerting a tumoricidal effect. The modality has been made less toxic because of new approaches to delivering TBI, such as fractionation, and partial organ shielding, Colleen Lawton, MD, professor at the Medical College of Wisconsin, Milwaukee, said at the 1998 Amer...

HERBERT S. SLSE, JACQUES GAUTHIEB, ROBERT BECKER AND JOHN Boz. c n H EMORRHAGE has been an important and ominous sign in victims of irradiation effects. Although its occurrence coincided with a period of intense thrombocytopenia, Allen and Jacobson1 in experimental observations in dogs observed a circulating heparin-like anticoagulant, and Allen2 concluded that it played an important role in th...

Total body irradiation (TBI) is a powerful but potentially hazardous tool used in the eradication of malignant cells and the suppression of the immune system to enable bone marrow engraftment. The occasion of its use is confined to bone marrow transplantation (BMT) in malignant disorders and some non-malignant haematological and metabolic conditions and is accompanied by high dose chemotherapy....

Total body irradiation (TBI) is a powerful but potentially hazardous tool used in the eradication of malignant cells and the suppression of the immune system to enable bone marrow engraftment. The occasion of its use is confined to bone marrow transplantation (BMT) in malignant disorders and some non-malignant haematological and metabolic conditions and is accompanied by high dose chemotherapy....

The determination of the dose delivered to the body during Total Body Irradiation (TBI) is not easy, as direct measurements are impossible. This article presents the intention to develop a systematic and simple method for absorbed dose determination in(60)Co TBI using mid plane dose factors (MDF) and external measurements, i.e. entrance and exit dose readings by semiconductor detectors. In orde...

The aim of this study was to investigate the dosimetric benefits between intensity-modulated radiotherapy (IMRT) and conventional radiotherapy (CR) among patients receiving breast-conserving surgery. A dosimetric comparison of IMRT and CR was evaluated in 20 patients with early-stage breast cancer using a three-dimensional treatment planning system. The prescribed mammary gland dose was complet...

us damages to the ovary storage and the matrix muscle state. some of these patients may admit to infertility clinics for having pregnancy and on the other hand hormonal administration for superovulation induction is a routine procedure in assisted reproduction technology (art) clinics.objective: this study aimed to investigate fertility and fetuses of hormone treated super ovulated female mice ...