candida species are the most common cause of opportunistic fungal infection worldwide. due to increasing resistance of fungi against conventional drugs, as well as their side effects, alternative natural products have become a renewed interest. in the current study, the anti-candida activities of scrophularia striata extract were examined. in this experimental study, microdilution assay and wel...

Inflammation is a part of the non-specific immune response which occurs in reaction to any type of injury. Medicinal mushrooms have had application in various disorders including cancer, liver injuries, inflammation and diabetes. In the present study, the anti-inflammatory effects of the aqueous extracts of medicinal mushrooms (Fomes fomentarius, Ganoderma applanatum and T...

Myocardial infarction is a common presentation of coronary artery disease and the leading cause of death worldwide. The present study was investigated potential resistance to ischemia-reperfusion (I/R) injuries following administration of methanolic (MeOH) extract of Scrophularia frigida (S. frigida) in isolated rat heart. Male Wistar rat hearts (n= 8-10) were isolated and allowed to equilibrat...

phenolic compounds including flavonoids and phenolic acids are plants secondary metabolites. due to their ability to act as antioxidant agents, there is a growing interest to use those components in traditional medicine for cancer prevention or treatment. the aim of this study was to measure the amounts of total phenolics and flavonoids as well as anti-proliferative effect of aqueous extract of...

Neutrophils, eosinophils and macrophages are cells that interact with invading parasites and naive hosts have been shown to have anti-parasitic activity. The initial reaction of these leukocytes is the generation of reactive oxygen species (ROS) to play in parasite expulsion. The present work was carried out to study the effect of total extract, scolex and membrane fractions from Cysticercus ce...

A total of 115 different plant extracts from our collection, representing 96 plant species, have been evaluated for in vitro antileishmanial activity against L. amazonensis promastigotes. In addition, the extracts were screened for cytotoxic activity against BALB/c mouse macrophages in order to assess a selectivity index. Crude extracts that showed a selectivity index (CC50 for macrophage / IC5...

background: the effects of aqueous extract of fadogia agrestis stem at the doses of 18, 36, and 72 mg/kg body weight on alloxan-induced toxicity was investigated in wistar rats. methods: in total, 35 rats of both sexes (132.80±7.22g) were randomized into five groups (a-e): animals in group a received 0.5 ml of distilled water orally on daily basis for 15 days while the alloxanized rats in group...

In the present investigation, effects of Ramalina capitata acetone extract on micronucleus distribution on human lymphocytes, on cholinesterase activity and antioxidant activity (by the CUPRAC method) were examined, for the first time as well as its HPLC profile. Additionally, total phenolic compounds (TPC), antioxidant properties (estimated via DPPH, ABTS and TRP assays) and antibacterial acti...

spasmolytic, antioxidant, anti-inflammatory and immuno-modulatory properties of ginger (rhizome of zingiber officinale roscoe) suggest that it may has beneficial effects on inflammatory bowel diseases. in the present study, the effect of this herbal extract on a model of acute colitis was evaluated. ginger hydroalcoholic extract with doses of 150, 350, 700 mg/kg, prednisolone (2 mg/kg), or vehi...

Objective: The aim of the study was to evaluate the anti-diabetic activity of methanolic extract of Coleus Vettiveroides Jacob in streptozotocin induced diabetic rats. Methods: Streptozotocin was used to induce diabetes mellitus. The anti-diabetic potential was assessed by determining oral glucose tolerance, fasting blood glucose, urine glucose estimation, changes in body weight, Liver function...