نتایج جستجو برای: toxicological properties

تعداد نتایج: 877045  

Journal: :iranian journal of basic medical sciences 0
hasan badie bostan department of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran soghra mehri department of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran pharmaceutical research center, mashhad university of medical sciences, mashhad, iran neurocognitive research center, mashhad university of medical sciences, mashhad, iran hossein hosseinzadeh department of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran pharmaceutical research center, mashhad university of medical sciences, mashhad, iran

saffron (crocus sativus l.) has been considered as a medicinal plant since ancient times and also widely used as food additive for its color, taste and odor. the pharmacological properties of saffron and its main constituents, crocin and safranal have been evaluated using different in vivo and in vitro models. additionally, other lines of studies have found toxicological effects of saffron.  ho...

2014
S. Chitra K. Jayaprakash

Effect of mercury on blood and its components of fish Labeo rohita was carried out in this study. The LC50 dose of 57.074 mg/L and mercuric chloride exposure for 96 h resulted in significant changes in the physico-chemical properties such as hemoglobin, osmotic fragility and blood cell counts. Further, mercury exposure also caused a considerable reduction in the sulf-hydryl group of glutathione...

2017
Mohammad Firoz Khan Md. Abdul Bari Md. Kamrul Islam Md. Shariful Islam Nusrat Nahar Mohammad A. Rashid

Article history: Received on: 26/01/2017 Accepted on: 22/03/2017 Available online: 30/05/2017 The purpose of the present study is to explore the physicochemical, pharmacokinetic and toxicological properties and to correlate the calculated physicochemical properties with the absorption and distribution profile of seven natural anti-tubercular agents such as 6a,7-dehydro-N-formylnornantenine (DNF...

2008
Fernando Aguilar Herman Autrup Susan Barlow Laurence Castle Riccardo Crebelli Wolfgang Dekant Karl-Heinz Engel Nathalie Gontard David Gott Sandro Grilli Rainer Gürtler John Christian Larsen Catherine Leclercq Jean-Charles Leblanc Xavier Malcata Wim Mennes Maria Rosaria Milana Iona Pratt Ivonne Rietjens Paul Tobback Fidel Toldrá

The European Food Safety Authority (EFSA) is asked to advise the Commission on substances used as flavouring substances or present in flavourings or present in other food ingredients with flavouring properties for which existing toxicological data indicate that restrictions of use or presence might be necessary to ensure safety of human health. In particular, EFSA is asked to advise the Commiss...

2017
David Lai

With the increasing use and development of engineered nanomaterials in electronics, pesticides, consumer products, and chemical and pharmaceutical industries, there is a growing concern about their potential risks to humans and the environment. The toxic effects of most nanomaterials have not been characterized, but it is generally believed that nanoparticles can have toxicological properties t...

2008
Fiona Geiser

Escitalopram is an antidepressant from the class called Selective Serotonin Reuptake Inhibitors (SSRI’s). SSRI’s were among the first pharmaceutical products commercialized as single enantiomers following a 1992 United States Food and Drug Administration (FDA) Policy Statement. The directive required a thorough investigation of the biological and toxicological properties of single enantiomers. ...

Journal: :Journal of hazardous materials 2012
Ruinan Zhang Yuhong Bai Bin Zhang Lingxin Chen Bing Yan

Widespread use of titania nanoparticles (TNPs) has caused a significant release of TNPs into the environment, increasing human exposure to TNPs. The potential toxicity of TNPs has become an urgent concern. Various models have been used to evaluate the toxic effects of TNPs, but the relationship between TNPs' toxicity and physicochemical properties is largely unknown. This review summarizes rele...

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